7XZX
Cryo-EM structure of the nucleosome in complex with p53 DNA-binding domain
Summary for 7XZX
Entry DOI | 10.2210/pdb7xzx/pdb |
EMDB information | 33533 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total) |
Functional Keywords | transcription factor, tumor-suppressor, gene regulation, gene reguration-dna complex, gene reguration/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 14 |
Total formula weight | 321939.83 |
Authors | Nishimura, M.,Nozawa, K.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2022-06-03, release date: 2022-10-12, Last modification date: 2024-07-03) |
Primary citation | Nishimura, M.,Takizawa, Y.,Nozawa, K.,Kurumizaka, H. Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1:pgac177-pgac177, 2022 Cited by PubMed: 36714865DOI: 10.1093/pnasnexus/pgac177 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.53 Å) |
Structure validation
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