7XZX

Cryo-EM structure of the nucleosome in complex with p53 DNA-binding domain

Summary for 7XZX

• Entry DOI: 10.2210/pdb7xzx/pdb
• EMDB information: 33533
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
• Functional Keywords: transcription factor, tumor-suppressor, gene regulation, gene reguration-dna complex, gene reguration/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 321939.83

Authors

Nishimura, M.,Nozawa, K.,Takizawa, Y.,Kurumizaka, H. (deposition date: 2022-06-03, release date: 2022-10-12, Last modification date: 2023-02-15)

• Primary citation: Nishimura, M.,Takizawa, Y.,Nozawa, K.,Kurumizaka, H.; Structural basis for p53 binding to its nucleosomal target DNA sequence.; Pnas Nexus, 1:pgac177-pgac177, 2022; PubMed: 36714865; DOI: 10.1093/pnasnexus/pgac177

Experimental method

ELECTRON MICROSCOPY (4.53 Å)