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PDB: 51586 件

4U5U
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U6F
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Crystal structure of T-2 toxin bound to the yeast 80S ribosome
分子名称: 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-28
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U1V
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Crystal structure of the E. coli ribosome bound to linopristin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
登録日2014-07-16
公開日2014-07-30
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U3N
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Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-22
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U58
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U4Z
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Crystal structure of Phyllanthoside bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U5O
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
8SK5
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Crystal structure of the SARS-CoV-2 neutralizing VHH 7A9 bound to the spike receptor binding domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, anti-SARS-CoV-2 receptor binding domain VHH
著者Noland, C.L, Pande, K, Zhang, L, Zhou, H, Galli, J, Eddins, M, Gomez-Llorente, Y.
登録日2023-04-18
公開日2023-08-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.011 Å)
主引用文献Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.
Sci Rep, 13, 2023
4WR5
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Crystal Structure of GST Mutated with Halogenated Tyrosine (7cGST-1)
分子名称: GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme, SULFATE ION
著者Akasaka, R, Kawazoe, M, Tomabechi, Y, Ohtake, K, Itagaki, T, Takemoto, C, Shirouzu, M, Yokoyama, S, Sakamoto, K.
登録日2014-10-23
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Protein stabilization utilizing a redefined codon
Sci Rep, 5, 2015
4UAQ
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Crystal structure of the accessory translocation ATPase, SecA2, from Mycobacterium tuberculosis
分子名称: Protein translocase subunit SecA 2
著者Swanson-Smith, S, Ioerger, T.R, Rigel, N.W, Miller, B.K, Braunstein, M, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2014-08-11
公開日2015-09-09
最終更新日2016-02-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Similarities and Differences between Two Functionally Distinct SecA Proteins, Mycobacterium tuberculosis SecA1 and SecA2.
J.Bacteriol., 198, 2015
4UAR
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Crystal structure of apo-CbbY from Rhodobacter sphaeroides
分子名称: GLYCEROL, Protein CbbY
著者Bracher, A, Sharma, A, Starling-Windhof, A, Hartl, F.U, Hayer-Hartl, M.
登録日2014-08-11
公開日2014-12-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Degradation of potent Rubisco inhibitor by selective sugar phosphatase.
Nat.Plants, 1, 2015
4UFR
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BU of 4ufr by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-2 (Fu1Fu2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Zebisch, M, Jones, E.Y.
登録日2015-03-18
公開日2015-07-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of R-Spondin 2 in Complex with the Ectodomains of its Receptors Lgr5 and Znrf3.
J.Struct.Biol., 191, 2015
8OQ5
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AApoAII amyloid fibril Morphology I (ex vivo)
分子名称: Apolipoprotein A-II
著者Andreotti, G, Schmidt, M, Faendrich, M.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
4UFT
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BU of 4uft by Molmil
Structure of the helical Measles virus nucleocapsid
分子名称: 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN
著者Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G.
登録日2015-03-19
公開日2015-04-29
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid.
Science, 348, 2015
8OQ4
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AApoAII amyloid fibril Morphology II (ex vivo)
分子名称: Apolipoprotein A-II
著者Andreotti, G, Schmidt, M, Faendrich, M.
登録日2023-04-11
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Insights into the Structural Basis of Amyloid Resistance Provided by Cryo-EM Structures of AApoAII Amyloid Fibrils.
J.Mol.Biol., 436, 2024
4U4T
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BU of 4u4t by Molmil
Structure of a nitrate/nitrite antiporter NarK in nitrate-bound inward-open state
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NITRATE ION, Nitrate/nitrite transporter NarK, ...
著者Fukuda, M, Takeda, H, Kato, H.E, Doki, S, Ito, K, Maturana, A.D, Ishitani, R, Nureki, O.
登録日2014-07-24
公開日2015-07-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
Nat Commun, 6, 2015
4U4U
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Crystal structure of Lycorine bound to the yeast 80S ribosome
分子名称: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4WJN
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BU of 4wjn by Molmil
Crystal structure of SUMO1 in complex with phosphorylated PML
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G.
登録日2014-10-01
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
4WJP
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Crystal Structure of SUMO1 in complex with phosphorylated Daxx
分子名称: Daxx, Small ubiquitin-related modifier 1
著者Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G.
登録日2014-10-01
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
4UBG
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Resting state of rat cysteine dioxygenase C93G variant
分子名称: Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION
著者Fellner, M, Tchesnokov, E.P, Jameson, G.N, Wilbanks, S.M.
登録日2014-08-13
公開日2014-11-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change.
Biochemistry, 53, 2014
4UBN
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KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 1.85 MGy TEMP 150K
分子名称: DIETHYL HYDROGEN PHOSPHATE, E3
著者Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G.
登録日2014-08-13
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography
Structure, 24, 2016
4UBI
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KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 3.70 MGy at 100K
分子名称: DIETHYL HYDROGEN PHOSPHATE, E3
著者Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G.
登録日2014-08-13
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography
Structure, 24, 2016
4UMM
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The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning
分子名称: 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP *AP*CP*TP*TP*GP*TP)-3', 5'-D(*DGP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*DAP *AP*CP*CP*CP*TP*T)-3', ...
著者Maletta, M, Orlov, I, Moras, D, Billas, I.M.L, Klaholz, B.P.
登録日2014-05-19
公開日2014-06-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (11.6 Å)
主引用文献The Palindromic DNA-Bound Usp-Ecr Nuclear Receptor Adopts an Asymmetric Organization with Allosteric Domain Positioning.
Nat.Commun., 5, 2014
4UHV
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The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System
分子名称: CHLORIDE ION, SODIUM ION, VGRG1, ...
著者Spinola-Amilibia, M, Davo-Siguero, I, Ruiz, F.M, Santillana, E, Medrano, F.J, Romero, A.
登録日2015-03-25
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of Vgrg1 from Pseudomonas Aeruginosa, the Needle Tip of the Bacterial Type Vi Secretion System
Acta Crystallogr.,Sect.D, 72, 2016
4UJ6
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Structure of surface layer protein SbsC, domains 1-6
分子名称: SURFACE LAYER PROTEIN
著者Dordic, A, Pavkov-Keller, T, Eder, M, Egelseer, E.M, Davis, K, Mills, D, Sleytr, U.B, Kuehlbrandt, W, Vonck, J, Keller, W.
登録日2015-04-08
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of Surface Layer Protein Sbsc, Domains 1-6
To be Published

224004

件を2024-08-21に公開中

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