4WR5

Crystal Structure of GST Mutated with Halogenated Tyrosine (7cGST-1)

Summary for 4WR5

Related4WR4
DescriptorGlutathione S-transferase class-mu 26 kDa isozyme, GLUTATHIONE, SULFATE ION, ... (4 entities in total)
Functional Keywordsthemostabilized structure, homodimeric, two domains, alfa/beta, alfa, detoxification, xenobiotic compounds, gutathione, 7 specfic sites, cytoplasmic, transferase
Biological sourceSchistosoma japonicum (Blood fluke)
Total number of polymer chains1
Total molecular weight28876.05
Authors
Primary citation
Ohtake, K.,Yamaguchi, A.,Mukai, T.,Kashimura, H.,Hirano, N.,Haruki, M.,Kohashi, S.,Yamagishi, K.,Murayama, K.,Tomabechi, Y.,Itagaki, T.,Akasaka, R.,Kawazoe, M.,Takemoto, C.,Shirouzu, M.,Yokoyama, S.,Sakamoto, K.
Protein stabilization utilizing a redefined codon
Sci Rep, 5:9762-9762, 2015
PubMed: 25985257 (PDB entries with the same primary citation)
DOI: 10.1038/srep09762
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236100.5%4.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution