4OJX
| crystal structure of yeast phosphodiesterase-1 in complex with GMP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3',5'-cyclic-nucleotide phosphodiesterase 1, GUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Tian, Y, Cui, W, Huang, M, Robinson, H, Wan, Y, Wang, Y, Ke, H. | 登録日 | 2014-01-21 | 公開日 | 2014-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate. Biochemistry, 53, 2014
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3QIM
| Histidine 416 of the periplamsic binding protein NikA is essential for nickel uptake in Escherichia coli | 分子名称: | ACETATE ION, GLYCEROL, Nickel-binding periplasmic protein, ... | 著者 | Cavazza, C, Martin, L, Laffly, E, Lebrette, H, Cherrier, M.V, Zeppieri, L, Richaud, P, Carriere, M, Fontecilla-Camps, J.C. | 登録日 | 2011-01-27 | 公開日 | 2011-03-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Histidine 416 of the periplasmic binding protein NikA is essential for nickel uptake in Escherichia coli Febs Lett., 585, 2011
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4OL8
| Ty3 reverse transcriptase bound to DNA/RNA | 分子名称: | 5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3', 5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3', Reverse transcriptase/ribonuclease H, ... | 著者 | Nowak, E, Miller, J.T, Bona, M.K, Studnicka, J, Szczepanowski, R.H, Jurkowski, J, Le Grice, S.F.J, Nowotny, M. | 登録日 | 2014-01-23 | 公開日 | 2014-03-05 | 最終更新日 | 2014-04-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry. Nat.Struct.Mol.Biol., 21, 2014
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1HM2
| ACTIVE SITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS | 分子名称: | 2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, CALCIUM ION, CHONDROITINASE AC, ... | 著者 | Huang, W, Boju, L, Tkalec, L, Su, H, Yang, H.O, Gunay, N.S, Linhardt, R.J, Kim, Y.S, Matte, A, Cygler, M. | 登録日 | 2000-12-04 | 公開日 | 2001-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis. Biochemistry, 40, 2001
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3VO9
| Staphylococcus aureus FtsZ apo-form (SeMet) | 分子名称: | Cell division protein FtsZ | 著者 | Matsui, T, Yamane, J, Mogi, N, Yao, M, Tanaka, I. | 登録日 | 2012-01-20 | 公開日 | 2012-08-29 | 最終更新日 | 2013-08-14 | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | 主引用文献 | Structural reorganization of the bacterial cell-division protein FtsZ from Staphylococcus aureus Acta Crystallogr.,Sect.D, 68, 2012
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4IWX
| Rimk structure at 2.85A | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Ribosomal protein S6 modification protein, ... | 著者 | Shi, D, Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M. | 登録日 | 2013-01-24 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.854 Å) | 主引用文献 | Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme. Proteins, 81, 2013
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6GYN
| Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2018-06-30 | 公開日 | 2019-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel To Be Published
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3CG0
| Crystal structure of signal receiver domain of modulated diguanylate cyclase from Desulfovibrio desulfuricans G20, an example of alternate folding | 分子名称: | Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor | 著者 | Patskovsky, Y, Bonanno, J.B, Romero, R, Gilmore, M, Chang, S, Groshong, C, Koss, J, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-03-04 | 公開日 | 2008-03-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of Signal Receiver Domain of Modulated Diguanylate Cyclase from Desulfovibrio desulfuricans. To be Published
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6HB8
| Crystal structure of OXA-517 beta-lactamase | 分子名称: | 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, Beta-lactamase, ... | 著者 | Raczynska, J.E, Dabos, L, Zavala, A, Retailleau, P, Iorga, B, Jaskolski, M, Naas, T. | 登録日 | 2018-08-09 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Genetic, biochemical and structural characterization of OXA-517, an OXA-48-like extended-spectrum cephalosporins and carbapenems-hydrolyzing beta-lactamase To Be Published
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6GYV
| Lariat-capping ribozyme (circular permutation form) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lariat-capping ribozyme, MAGNESIUM ION, ... | 著者 | Masquida, B, Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E. | 登録日 | 2018-07-02 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.50003624 Å) | 主引用文献 | Speciation of a group I intron into a lariat capping ribozyme. Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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3QSL
| Structure of CAE31940 from Bordetella bronchiseptica RB50 | 分子名称: | CITRIC ACID, Putative exported protein | 著者 | Bajor, J, Kagan, O, Chruszcz, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-02-21 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of pyrimidine/thiamin biosynthesis precursor-like domain-containing protein CAE31940 from proteobacterium Bordetella bronchiseptica RB50, and evolutionary insight into the NMT1/THI5 family. J Struct Funct Genomics, 15, 2014
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6TPB
| NMR structure of the apo-form of Pseudomonas fluorescens CopC | 分子名称: | Putative copper resistance protein | 著者 | Persson, K.C, Mayzel, M, Karlsson, B.G, Peciulyte, A, Olsson, L, Wittung Stafshede, P, Salomon Johansen, K, Horvath, I. | 登録日 | 2019-12-13 | 公開日 | 2021-01-13 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of Pseudomonas fluorescens CopC To Be Published
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4OPP
| Crystal structure of the ternary complex of camel peptidoglycan recognition protein PGRP-S with 11-cyclohexylundecanoic acid and N- acetylglucosamine at 2.30 A resolution | 分子名称: | 11-cyclohexylundecanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Yamini, S, Sharma, P, Yadav, S.P, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2014-02-06 | 公開日 | 2014-03-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the ternary complex of camel peptidoglycan recognition protein PGRP-S with 11-cyclohexylundecanoic acid and N- acetylglucosamine at 2.30 A resolution To be Published
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4IUZ
| High resolution crystal structure of racemic ester insulin | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... | 著者 | Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. | 登録日 | 2013-01-22 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4OC7
| Retinoic acid receptor alpha in complex with (E)-3-(3'-allyl-6-hydroxy-[1,1'-biphenyl]-3-yl)acrylic acid and a fragment of the coactivator TIF2 | 分子名称: | (2E)-3-[6-hydroxy-3'-(prop-2-en-1-yl)biphenyl-3-yl]prop-2-enoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Leysen, S, Scheepstra, M, Brunsveld, L, Milroy, L.G, Ottmann, C. | 登録日 | 2014-01-08 | 公開日 | 2014-10-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A natural-product switch for a dynamic protein interface. Angew.Chem.Int.Ed.Engl., 53, 2014
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4OPY
| Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation | 分子名称: | CALCIUM ION, Extended spectrum beta-lactamase TEM-63, SULFATE ION, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-07 | 公開日 | 2015-05-20 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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4OCD
| In and Out the minor groove: Interaction of an AT rich-DNA with the CD27 drug | 分子名称: | N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine, d(AAAATTTT) | 著者 | Acosta-Reyes, F.J, Dardonville, C, de Koning, H.P, Natto, M, Subirana, J.A, Campos, J.L. | 登録日 | 2014-01-08 | 公開日 | 2014-06-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27 Acta Crystallogr.,Sect.D, D70, 2014
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4OQO
| Crystal structure of the tryptic generated iron-free C-lobe of bovine Lactoferrin at 2.42 Angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lactotransferrin | 著者 | Singh, A, Rastogi, N, Pandey, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2014-02-10 | 公開日 | 2014-03-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut. Febs J., 281, 2014
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5A0C
| Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor | 分子名称: | (6S)-6-(4-cyano-2-methylsulfonyl-phenyl)-4-methyl-2-oxidanylidene-3-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carbonitrile, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | vonNussbaum, F, Li, V.M.-J, Allerheiligen, S, Anlauf, S, Baerfacker, L, Bechem, M, Delbeck, M, Fitzgerald, M.F, Gerisch, M, Gielen-Haertwig, H, Haning, H, Karthaus, D, Lang, D, Lustig, K, Meibom, D, Mittendorf, J, Rosentreter, U, Schaefer, M, Schaefer, S, Schamberger, J, Telan, L.A, Tersteegen, A. | 登録日 | 2015-04-17 | 公開日 | 2015-08-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem, 10, 2015
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3QN3
| Phosphopyruvate hydratase from Campylobacter jejuni. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Enolase, GLYCEROL, ... | 著者 | Osipiuk, J, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-02-07 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Phosphopyruvate hydratase from Campylobacter jejuni. To be Published
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3Q5L
| Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin | 分子名称: | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-{[2-(pyrrolidin-1-yl)ethyl]amino}-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, Heat shock protein 83-1 | 著者 | Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | 登録日 | 2010-12-28 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin. To be Published
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1KY8
| Crystal Structure of the Non-phosphorylating glyceraldehyde-3-phosphate Dehydrogenase | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, glyceraldehyde-3-phosphate dehydrogenase | 著者 | Pohl, E, Brunner, N, Wilmanns, M, Hensel, R. | 登録日 | 2002-02-04 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Crystal Structure of the Allosteric Non-phosphorylating
glyceraldehyde-3-phosphate Dehydrogenase from the Hyperthermophilic
Archaeum Thermoproteus tenax J.Biol.Chem., 277, 2002
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3CJZ
| Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m22G:A pairs | 分子名称: | RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3') | 著者 | Pallan, P.S, Kreutz, C, Bosio, S, Micura, R, Egli, M. | 登録日 | 2008-03-14 | 公開日 | 2008-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. Rna, 14, 2008
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4IZI
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6EO1
| The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H. | 登録日 | 2017-10-08 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (4.5 Å) | 主引用文献 | High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer. Structure, 26, 2018
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