4OJX

crystal structure of yeast phosphodiesterase-1 in complex with GMP

Summary for 4OJX

• Entry DOI: 10.2210/pdb4ojx/pdb
• Related: 4OJV
• Descriptor: 3',5'-cyclic-nucleotide phosphodiesterase 1, (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, ... (5 entities in total)
• Functional Keywords: phosphodiesterase, cgmp and camp, yeast pde, dual specificity, hydrolase
• Biological source: Saccharomyces cerevisiae S288C
• Total number of polymer chains: 1
• Total formula weight: 42682.21

Authors

Tian, Y.,Cui, W.,Huang, M.,Robinson, H.,Wan, Y.,Wang, Y.,Ke, H. (deposition date: 2014-01-21, release date: 2014-12-03, Last modification date: 2024-02-28)

• Primary citation: Tian, Y.,Cui, W.,Huang, M.,Robinson, H.,Wan, Y.,Wang, Y.,Ke, H.; Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate.; Biochemistry, 53:4938-4945, 2014; PubMed: 25050706; DOI: 10.1021/bi500406h

Experimental method

X-RAY DIFFRACTION (1.31 Å)