4OCD

In and Out the minor groove: Interaction of an AT rich-DNA with the CD27 drug

Summary for 4OCD

Entry DOI	10.2210/pdb4ocd/pdb
Descriptor	d(AAAATTTT), N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine (3 entities in total)
Functional Keywords	dna minor groove binding drugs, all-at dna, dicationic drug, imidazoline drug, dna
Total number of polymer chains	3
Total formula weight	8280.14
Authors	Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L. (deposition date: 2014-01-08, release date: 2014-06-11, Last modification date: 2024-02-28)
Primary citation	Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L. In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27 Acta Crystallogr.,Sect.D, D70:1614-1621, 2014 Cited by PubMed: 24914972 DOI: 10.1107/S139900471400697X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation