8CF0
| Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2 | 分子名称: | 9-chloranyl-1,4-dihydropyrazino[2,3-c]quinoline-2,3-dione, DIMETHYL SULFOXIDE, DNA cross-link repair 1A protein, ... | 著者 | Newman, J.A, Yosaatmadja, Y, Baddock, H.T, Bielinski, M, von Delft, F, Bountra, C, McHugh, P.J, Schofield, C.J, Gileadi, O. | 登録日 | 2023-02-02 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2 To Be Published
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5J1B
| structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - WT. | 分子名称: | Cell wall assembly regulator SMI1 | 著者 | Maveyraud, L, Batista, M, Martin-yken, H, Francois, J.M, Zerbib, D, Mourey, L. | 登録日 | 2016-03-29 | 公開日 | 2017-04-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and biophysical characterization of Knr4, an intrinsically disordered hub protein form Saccharomyces cerevisiae To Be Published
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7LK9
| Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC | 分子名称: | COV107-23 heavy chain, COVD21-C8 light chain | 著者 | Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C. | 登録日 | 2021-02-01 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain. Nat Commun, 12, 2021
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7LKA
| Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 | 分子名称: | ACETATE ION, COV107-23 heavy chain, COV107-23 light chain | 著者 | Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C. | 登録日 | 2021-02-02 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain. Nat Commun, 12, 2021
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5J1O
| Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat | 分子名称: | Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat | 著者 | Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M. | 登録日 | 2016-03-29 | 公開日 | 2016-06-08 | 最終更新日 | 2019-10-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a low-population binding intermediate in protein-RNA recognition. Proc.Natl.Acad.Sci.USA, 113, 2016
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7QAO
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5IUQ
| Galectin-3c in complex with Bisamido-thiogalactoside derivative 4 | 分子名称: | 3-deoxy-3-[(2,3,5,6-tetrafluoro-4-methoxybenzene-1-carbonyl)amino]-beta-D-galactopyranosyl 3-deoxy-3-[(2,3,5,6-tetrafluoro-4-methoxybenzene-1-carbonyl)amino]-1-thio-beta-D-galactopyranoside, Galectin-3 | 著者 | Noresson, A.-L, Aurelius, O, Oberg, C.T, Engstrom, O, Sundin, A.P, Hakansson, M, Logan, D.T, Leffler, H, Nilsson, U.J. | 登録日 | 2016-03-18 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.121 Å) | 主引用文献 | Controlling protein:ligand complex conformation through tuning of arginine-arene interactions: Synthetic and structural studies with 3-benzamido-2-sulfo-galactosides as galectin-3 ligands To Be Published
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2MOR
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5J1Y
| Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with 1-(pyrrolidin-1-yl)-3-(tetrahydrofuran-3-yl)propan-1-one at 1.81A resolution | 分子名称: | 3-[(3S)-oxolan-3-yl]-1-(pyrrolidin-1-yl)propan-1-one, EthR | 著者 | Blaszczyk, M, Surade, S, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2016-03-29 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem. Biol., 12, 2017
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5U40
| Human PPARdelta ligand-binding domain in complexed with specific agonist 15 | 分子名称: | 6-[2-({benzyl[4-(furan-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... | 著者 | Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. | 登録日 | 2016-12-03 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6GV1
| Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment | 分子名称: | Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, ... | 著者 | Nagarathinam, K, Parthier, C, Stubbs, M.T, Tanabe, M. | 登録日 | 2018-06-20 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism. Nat Commun, 9, 2018
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5ITT
| Crystal Structure of Human NEIL1 bound to duplex DNA containing THF | 分子名称: | DNA (26-MER), Endonuclease 8-like 1, GLYCEROL | 著者 | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | 登録日 | 2016-03-17 | 公開日 | 2016-07-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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5EOI
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5NXF
| Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, residues 795 to 1289, at 1.9 Angstrom. | 分子名称: | ACETATE ION, GLYCEROL, Long-tail fiber proximal subunit, ... | 著者 | Namura, M, van Raaij, M.J, Kanamaru, S. | 登録日 | 2017-05-10 | 公開日 | 2017-07-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Carboxy-Terminal Region of the Bacteriophage T4 Proximal Long Tail Fiber Protein Gp34. Viruses, 9, 2017
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7QWZ
| Full capsid of Saccharomyces cerevisiae virus L-BCLa | 分子名称: | Major capsid protein | 著者 | Grybchuk, D, Prochazkova, M, Fuzik, T, Konovalovas, A, Serva, S, Yurchenko, V, Plevka, P. | 登録日 | 2022-01-26 | 公開日 | 2022-09-07 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly. Commun Biol, 5, 2022
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5EL6
| Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. | 登録日 | 2015-11-04 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
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5IVG
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1BLF
| STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Moore, S.A, Anderson, B.F, Groom, C.R, Haridas, M, Baker, E.N. | 登録日 | 1997-08-20 | 公開日 | 1997-12-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution. J.Mol.Biol., 274, 1997
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5J5H
| X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(2-methoxyphenyl)-N4,N4-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(2-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine, Acetylcholine-binding protein, ... | 著者 | Kaczanowska, K, Harel, M, Camacho Hernandez, A.G, Taylor, P. | 登録日 | 2016-04-02 | 公開日 | 2017-03-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017
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5EUG
| CRYSTALLOGRAPHIC AND ENZYMATIC STUDIES OF AN ACTIVE SITE VARIANT H187Q OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE: CRYSTAL STRUCTURES OF MUTANT H187Q AND ITS URACIL COMPLEX | 分子名称: | PROTEIN (GLYCOSYLASE), URACIL | 著者 | Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. | 登録日 | 1998-12-27 | 公開日 | 1999-07-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited. Proteins, 35, 1999
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8A0K
| crystal structure of the kinetoplastid kinetochore protein Trypanosoma brucei KKT3 Divergent Polo-Box domain | 分子名称: | DI(HYDROXYETHYL)ETHER, Protein kinase, putative | 著者 | Ishii, M, Ludzia, P, Marciano, G, Allen, W, Nerusheva, O.O, Akiyoshi, B. | 登録日 | 2022-05-27 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei. Mol.Biol.Cell, 33, 2022
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7QS8
| Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | 分子名称: | Protein Tax-1, Protein scribble homolog | 著者 | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | 登録日 | 2022-01-13 | 公開日 | 2022-09-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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7QWX
| Empty capsid of Saccharomyces cerevisiae virus L-BCLa | 分子名称: | Major capsid protein | 著者 | Grybchuk, D, Prochazkova, M, Fuzik, T, Konovalovas, A, Serva, S, Yurchenko, V, Plevka, P. | 登録日 | 2022-01-26 | 公開日 | 2022-09-07 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly. Commun Biol, 5, 2022
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8A0J
| Crystal structure of the kinetoplastid kinetochore protein Trypanosoma congolense KKT2 divergent polo-box domain | 分子名称: | Uncharacterized protein TCIL3000_11_11110 | 著者 | Ishii, M, Ludzia, P, Marciano, G, Allen, W, Nerusheva, O, Akiyoshi, B. | 登録日 | 2022-05-27 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Divergent polo boxes in KKT2 bind KKT1 to initiate the kinetochore assembly cascade in Trypanosoma brucei. Mol.Biol.Cell, 33, 2022
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7QRS
| Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | 分子名称: | ACETATE ION, GLYCEROL, Protein Tax-1, ... | 著者 | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | 登録日 | 2022-01-12 | 公開日 | 2022-09-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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