5IVG
Crystal structure of Aspergillus terreus aristolochene synthase N299A complexed with farnesyl thiolodiphosphate
Summary for 5IVG
| Entry DOI | 10.2210/pdb5ivg/pdb |
| Descriptor | Aristolochene synthase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | lyase, terpene cyclases, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Aspergillus terreus |
| Total number of polymer chains | 4 |
| Total formula weight | 146874.99 |
| Authors | Chen, M.,Christianson, D.W. (deposition date: 2016-03-20, release date: 2016-05-25, Last modification date: 2023-09-27) |
| Primary citation | Chen, M.,Chou, W.K.,Al-Lami, N.,Faraldos, J.A.,Allemann, R.K.,Cane, D.E.,Christianson, D.W. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry, 55:2864-2874, 2016 Cited by PubMed: 27172425DOI: 10.1021/acs.biochem.6b00343 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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