5IVG

Crystal structure of Aspergillus terreus aristolochene synthase N299A complexed with farnesyl thiolodiphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008299	biological_process	isoprenoid biosynthetic process
A	0010333	molecular_function	terpene synthase activity
A	0016829	molecular_function	lyase activity
A	0016838	molecular_function	carbon-oxygen lyase activity, acting on phosphates
A	0045483	molecular_function	aristolochene synthase activity
A	0046872	molecular_function	metal ion binding
B	0008299	biological_process	isoprenoid biosynthetic process
B	0010333	molecular_function	terpene synthase activity
B	0016829	molecular_function	lyase activity
B	0016838	molecular_function	carbon-oxygen lyase activity, acting on phosphates
B	0045483	molecular_function	aristolochene synthase activity
B	0046872	molecular_function	metal ion binding
C	0008299	biological_process	isoprenoid biosynthetic process
C	0010333	molecular_function	terpene synthase activity
C	0016829	molecular_function	lyase activity
C	0016838	molecular_function	carbon-oxygen lyase activity, acting on phosphates
C	0045483	molecular_function	aristolochene synthase activity
C	0046872	molecular_function	metal ion binding
D	0008299	biological_process	isoprenoid biosynthetic process
D	0010333	molecular_function	terpene synthase activity
D	0016829	molecular_function	lyase activity
D	0016838	molecular_function	carbon-oxygen lyase activity, acting on phosphates
D	0045483	molecular_function	aristolochene synthase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 701

Chain	Residue
A	ASP84
A	MG702
A	FPS704
A	HOH830
A	HOH852
A	HOH980

---

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 702

Chain	Residue
A	HOH834
A	HOH940
A	HOH943
A	HOH980
A	ASP84
A	MG701
A	FPS704

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG A 703

Chain	Residue
A	ASN213
A	SER217
A	GLU221
A	FPS704
A	HOH881

---

site_id	AC4
Number of Residues	19
Details	binding site for residue FPS A 704

Chain	Residue
A	TYR61
A	PHE81
A	ASP84
A	PHE147
A	ARG169
A	ASN213
A	SER217
A	LYS220
A	GLU221
A	TRP302
A	ARG308
A	TYR309
A	MG701
A	MG702
A	MG703
A	HOH830
A	HOH852
A	HOH953
A	HOH980

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 705

Chain	Residue
A	TYR216
A	GLN304
A	SER310
A	HOH814
A	HOH905

---

site_id	AC6
Number of Residues	6
Details	binding site for residue MG B 701

Chain	Residue
B	ASP84
B	MG702
B	FPS704
B	HOH843
B	HOH879
B	HOH993

---

site_id	AC7
Number of Residues	7
Details	binding site for residue MG B 702

Chain	Residue
B	ASP84
B	MG701
B	FPS704
B	HOH840
B	HOH971
B	HOH993
B	HOH1054

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MG B 703

Chain	Residue
B	ASN213
B	SER217
B	GLU221
B	FPS704
B	HOH885

---

site_id	AC9
Number of Residues	20
Details	binding site for residue FPS B 704

Chain	Residue
B	TYR61
B	PHE81
B	ASP84
B	PHE147
B	ARG169
B	ASN213
B	SER217
B	LYS220
B	GLU221
B	TRP302
B	ARG308
B	TYR309
B	MG701
B	MG702
B	MG703
B	HOH840
B	HOH843
B	HOH857
B	HOH879
B	HOH993

---

site_id	AD1
Number of Residues	9
Details	binding site for residue GOL B 705

Chain	Residue
B	ARG107
B	GLU142
B	ARG149
B	HOH854
B	HOH930
C	ARG197
C	GLU200
C	LEU275
C	HOH939

---

site_id	AD2
Number of Residues	6
Details	binding site for residue MG C 701

Chain	Residue
C	ASP84
C	MG702
C	FPS704
C	HOH809
C	HOH889
C	HOH968

---

site_id	AD3
Number of Residues	7
Details	binding site for residue MG C 702

Chain	Residue
C	HOH906
C	HOH930
C	HOH968
C	ASP84
C	MG701
C	FPS704
C	HOH822

---

site_id	AD4
Number of Residues	5
Details	binding site for residue MG C 703

Chain	Residue
C	ASN213
C	SER217
C	GLU221
C	FPS704
C	HOH878

---

site_id	AD5
Number of Residues	19
Details	binding site for residue FPS C 704

Chain	Residue
C	TYR61
C	PHE81
C	ASP84
C	PHE147
C	ARG169
C	ASN213
C	SER217
C	LYS220
C	GLU221
C	ARG308
C	TYR309
C	MG701
C	MG702
C	MG703
C	HOH809
C	HOH822
C	HOH839
C	HOH889
C	HOH968

---

site_id	AD6
Number of Residues	8
Details	binding site for residue GOL C 705

Chain	Residue
B	ARG197
B	LEU280
B	HOH985
C	ARG107
C	GLU142
C	ARG149
C	HOH853
C	HOH980

---

site_id	AD7
Number of Residues	6
Details	binding site for residue MG D 701

Chain	Residue
D	ASP84
D	MG702
D	FPS704
D	HOH843
D	HOH844
D	HOH848

---

site_id	AD8
Number of Residues	7
Details	binding site for residue MG D 702

Chain	Residue
D	ASP84
D	MG701
D	FPS704
D	HOH823
D	HOH848
D	HOH873
D	HOH944

---

site_id	AD9
Number of Residues	5
Details	binding site for residue MG D 703

Chain	Residue
D	ASN213
D	SER217
D	GLU221
D	FPS704
D	HOH841

---

site_id	AE1
Number of Residues	20
Details	binding site for residue FPS D 704

Chain	Residue
D	TYR61
D	PHE81
D	ASP84
D	PHE147
D	ARG169
D	VAL173
D	ASN213
D	SER217
D	LYS220
D	GLU221
D	ARG308
D	TYR309
D	MG701
D	MG702
D	MG703
D	HOH805
D	HOH823
D	HOH843
D	HOH844
D	HOH848

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17261032","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18385128","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17261032","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18385128","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BNX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18385128","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BNX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---