5FV0
| The cytoplasmic domain of EssC | 分子名称: | 3'-O-[2-(METHYLAMINO)BENZOYL]ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), ADENOSINE-5'-TRIPHOSPHATE, ESX secretion system protein EccC, ... | 著者 | Zoltner, M, Ng, W.M.A.V, Palmer, T, Hunter, W.N. | 登録日 | 2016-02-01 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system. Biochem. J., 473, 2016
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7QGP
| STK10 (LOK) bound to Macrocycle CKJB51 | 分子名称: | 1,2-ETHANEDIOL, 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea, CHLORIDE ION, ... | 著者 | Berger, B.-T, Schroeder, M, Kraemer, A, Schwalm, M.P, Kurz, C.G, Amrhein, J.A, Hanke, T, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-12-09 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | STK10 bound to CKJB51 To Be Published
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5IK1
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5FM0
| Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis (PtCl4 derivative) | 分子名称: | 6-CARBOXYHEXANOATE--COA LIGASE, MAGNESIUM ION, PIMELOYL-AMP, ... | 著者 | Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. | 登録日 | 2015-10-29 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters. Nat. Chem. Biol., 13, 2017
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5FRS
| Structure of the Pds5-Scc1 complex and implications for cohesin function | 分子名称: | SISTER CHROMATID COHESION PROTEIN 1, SISTER CHROMATID COHESION PROTEIN PDS5 | 著者 | Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D. | 登録日 | 2015-12-22 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (4.073 Å) | 主引用文献 | Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function Cell Rep., 14, 2016
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5G0G
| Crystal structure of Danio rerio HDAC6 CD1 in complex with trichostatin A | 分子名称: | CHLORIDE ION, HDAC6, SODIUM ION, ... | 著者 | Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P. | 登録日 | 2016-03-18 | 公開日 | 2016-07-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12, 2016
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8C84
| Crystal structure of MADS-box/MEF2D N-terminal domain complex | 分子名称: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), MEF2D protein | 著者 | Chinellato, M, Carli, A, Perin, S, Mazzoccato, Y, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L. | 登録日 | 2023-01-18 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA. J.Mol.Biol., 436, 2024
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5FKQ
| Unraveling the first step of xyloglucan degradation by the soil saprophyte Cellvibrio japonicus through the functional and structural characterization of a potent GH74 endo-xyloglucanase | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, ENDO-1,4-BETA-GLUCANASE/XYLOGLUCANASE, ... | 著者 | Attia, M, Stepper, J, Davies, G.J, Brumer, H. | 登録日 | 2015-10-19 | 公開日 | 2015-11-04 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Functional and Structural Characterization of a Potent Gh74 Endo-Xyloglucanase from the Soil Saprophyte Cellvibrio Japonicus Unravels the First Step of Xyloglucan Degradation. FEBS J., 283, 2016
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7QID
| tentative model of the human insulin receptor ectodomain bound by three insulin | 分子名称: | Insulin, Insulin receptor, Isoform Short of Insulin receptor | 著者 | Gutman, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | 登録日 | 2021-12-14 | 公開日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain J Cell Biol, 219, 2020
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5FSM
| MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, DIMETHYL SULFOXIDE, ... | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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8CD1
| 70S-PHIKZ014 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Gerovac, M, Vogel, J. | 登録日 | 2023-01-29 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Phage proteins target and co-opt host ribosomes immediately upon infection. Nat Microbiol, 9, 2024
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7QWQ
| Ternary complex of ribosome nascent chain with SRP and NAC | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | 登録日 | 2022-01-25 | 公開日 | 2022-03-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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5FSO
| MTH1 substrate recognition: Complex with a methylaminopyrimidinedione. | 分子名称: | 6-(METHYLAMINO)-1H-PYRIMIDINE-2,4-DIONE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, ... | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | MTH1 Substrate Recognition--An Example of Specific Promiscuity. PLoS ONE, 11, 2016
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5FSI
| MTH1 substrate recognition: Complex with 8-oxo-dGTP. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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8C3A
| Crystal structure of ailanthone bound to the Candida albicans 80S ribosome | 分子名称: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | 登録日 | 2022-12-23 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | New crystal system to promote screening for new eukaryotic inhibitors To Be Published
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5FXS
| IGFR-1R complex with a pyrimidine inhibitor. | 分子名称: | 2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide, ACETATE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | 著者 | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | 登録日 | 2016-03-02 | 公開日 | 2016-10-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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7QHY
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7Q82
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5U3W
| Human PPARdelta ligand-binding domain in complexed with specific agonist 7 | 分子名称: | 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(cyclopropyl)amino]methyl}phenoxy)hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... | 著者 | Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. | 登録日 | 2016-12-03 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5IX8
| Crystal structure of sugar ABC transport system, substrate-binding protein from Bordetella parapertussis 12822 | 分子名称: | 1,2-ETHANEDIOL, Putative sugar ABC transport system, substrate-binding protein, ... | 著者 | Chang, C, Cuff, M, Joachimiak, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-03-23 | 公開日 | 2016-04-06 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of sugar ABC transport system, substrate-binding protein from Bordetella parapertussis 12822 To Be Published
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8C8S
| Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 21). | 分子名称: | (2~{R})-3-[6-chloranyl-2-(prop-2-enylamino)quinazolin-4-yl]-2-methyl-~{N}-oxidanyl-propanamide, DNA cross-link repair 1A protein, ZINC ION | 著者 | Yosaatmadja, Y, Newman, J.A, Baddock, H.T, Bielinski, M, von Delft, F, Bountra, C, McHugh, P.J, Schofield, C.J, Gileadi, O. | 登録日 | 2023-01-20 | 公開日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 21). To Be Published
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7Q7Y
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5TSB
| Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+ | 分子名称: | CADMIUM ION, Membrane protein | 著者 | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | 登録日 | 2016-10-28 | 公開日 | 2017-09-20 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
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5U4J
| Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ... | 著者 | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | 登録日 | 2016-12-04 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome. Nature, 541, 2017
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5FSK
| MTH1 substrate recognition: Complex with 8-oxo-dGTP. | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-ADENOSINE-5'-TRIPHOSPHATE, ACETATE ION | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity. Plos One, 11, 2016
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