7QGP

STK10 (LOK) bound to Macrocycle CKJB51

Summary for 7QGP

• Entry DOI: 10.2210/pdb7qgp/pdb
• Descriptor: Serine/threonine-protein kinase 10, 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: kinase, stk10, lok, macrocycle, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 34830.98

Authors

Berger, B.-T.,Schroeder, M.,Kraemer, A.,Schwalm, M.P.,Kurz, C.G.,Amrhein, J.A.,Hanke, T.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2021-12-09, release date: 2022-01-26, Last modification date: 2024-01-31)

• Primary citation: Schroeder, M.,Berger, B.T.,Kraemer, A.,Kurz, C.G.,Amrhein, J.A.,Hanke, T.,Knapp, S.,Structural Genomics Consortium (SGC); STK10 bound to CKJB51; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)