7QGP
STK10 (LOK) bound to Macrocycle CKJB51
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 10 | polymer | 302 | 34240.5 | 1 | UniProt (O94804) Pfam (PF00069) | Homo sapiens (human) | Lymphocyte-oriented kinase |
| 2 | B (A) | 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea | non-polymer | 493.0 | 1 | Chemie (DJ8) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
| Ala 272 | Lys 272 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34240.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 590.5 | |
| All* | Total formula weight | 34831.0 |
