5FSO
MTH1 substrate recognition: Complex with a methylaminopyrimidinedione.
Summary for 5FSO
| Entry DOI | 10.2210/pdb5fso/pdb |
| Related | 5FSI 5FSK 5FSL 5FSM 5FSN |
| Descriptor | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, 6-(METHYLAMINO)-1H-PYRIMIDINE-2,4-DIONE, ... (5 entities in total) |
| Functional Keywords | hydrolase, nudt1 |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Isoform p18: Cytoplasm. Isoform p26: Cytoplasm: P36639 |
| Total number of polymer chains | 1 |
| Total formula weight | 18327.90 |
| Authors | Nissink, J.W.M.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Phillips, C.,Winter, J.J. (deposition date: 2016-01-06, release date: 2017-01-18, Last modification date: 2017-03-22) |
| Primary citation | Nissink, J.W.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Winter-Holt, J.J. MTH1 Substrate Recognition--An Example of Specific Promiscuity. PLoS ONE, 11:e0151154-e0151154, 2016 Cited by PubMed: 26999531DOI: 10.1371/journal.pone.0151154 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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