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5FSO

MTH1 substrate recognition: Complex with a methylaminopyrimidinedione.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASEpolymer15617971.51UniProt (P36639)
Pfam (PF00293)
HOMO SAPIENS (HUMAN)2-HYDROXY-DATP DIPHOSPHATASE, 8-OXO-DGTPASE, NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 1, NUDIX MOTIF 1, MTH1
2B
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
3C
(A)
6-(METHYLAMINO)-1H-PYRIMIDINE-2,4-DIONEnon-polymer141.11Chemie (S76)
4D, E
(A)
DIMETHYL SULFOXIDEnon-polymer78.12Chemie (DMS)
5F
(A)
waterwater18.0164Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17971.5
Non-Polymers*Number of molecules4
Total formula weight356.4
All*Total formula weight18327.9
*Water molecules are not included.

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PDB entries from 2025-07-30

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