5FSM

MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide.

Summary for 5FSM

• Entry DOI: 10.2210/pdb5fsm/pdb
• Related: 5FSI 5FSK 5FSL 5FSN 5FSO
• Descriptor: 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, N-(1-METHYLBENZIMIDAZOL-5-YL)ACETAMIDE, ... (5 entities in total)
• Functional Keywords: hydrolase, nudt1
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Isoform p18: Cytoplasm. Isoform p26: Cytoplasm: P36639
• Total number of polymer chains: 1
• Total formula weight: 18454.12

Authors

Nissink, J.W.M.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Phillips, C.,Winter, J.J. (deposition date: 2016-01-06, release date: 2016-07-20, Last modification date: 2017-01-25)

• Primary citation: Nissink, J.W.M.,Bista, M.,Breed, J.,Carter, N.,Embrey, K.,Read, J.,Winter-Holt, J.J.; Mth1 Substrate Recognition--an Example of Specific Promiscuity.; Plos One, 11:51154-, 2016; PubMed: 26999531; DOI: 10.1371/JOURNAL.PONE.0151154

Experimental method

X-RAY DIFFRACTION (1.67 Å)