6QHL
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![BU of 6qhl by Molmil](/molmil-images/mine/6qhl) | 14-3-3 sigma with RelA/p65 binding site pS45 | Descriptor: | 14-3-3 protein sigma, GLYCEROL, Transcription factor p65 | Authors: | Wolter, M, Ottmann, C. | Deposit date: | 2019-01-16 | Release date: | 2020-05-13 | Last modified: | 2020-12-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products. J.Am.Chem.Soc., 142, 2020
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6QJV
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7UV5
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![BU of 7uv5 by Molmil](/molmil-images/mine/7uv5) | The crystal structure of Papain-Like Protease of SARS CoV-2, C111S/D286N mutant, in complex with a Lys48-linked di-ubiquitin | Descriptor: | 1,2-ETHANEDIOL, Papain-like protease nsp3, Ubiquitin, ... | Authors: | Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-04-29 | Release date: | 2022-05-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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1ZG7
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![BU of 1zg7 by Molmil](/molmil-images/mine/1zg7) | Crystal Structure of 2-(5-{[amino(imino)methyl]amino}-2-chlorophenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B | Descriptor: | 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B | Authors: | Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M. | Deposit date: | 2005-04-20 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b. Biochemistry, 44, 2005
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6WY4
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![BU of 6wy4 by Molmil](/molmil-images/mine/6wy4) | Crystal Structure of Wild Type Class D beta-lactamase from Clostridium difficile 630 | Descriptor: | Beta-lactamase, DI(HYDROXYETHYL)ETHER, SODIUM ION | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Rosas-Lemus, M, Jedrzejczak, R, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-05-12 | Release date: | 2020-05-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Wild Type Class D beta-lactamase from Clostridium difficile 630 To Be Published
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6QBI
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![BU of 6qbi by Molmil](/molmil-images/mine/6qbi) | NMR structure of BB_P28, Borrelia burgdorferi outer surface lipoprotein | Descriptor: | Surface protein, mlp lipoprotein family | Authors: | Fridmanis, J, Otikovs, M, Brangulis, K, Jaudzems, K. | Deposit date: | 2018-12-21 | Release date: | 2020-01-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family. Proteins, 2020
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4KEA
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![BU of 4kea by Molmil](/molmil-images/mine/4kea) | Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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6PVT
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![BU of 6pvt by Molmil](/molmil-images/mine/6pvt) | Influenza B M2 Proton Channel in the Open State - SSNMR Structure at pH 4.5 | Descriptor: | BM2 protein | Authors: | Mandala, V.S, Loftis, A.R, Shcherbakov, A.S, Pentelute, B.L, Hong, M. | Deposit date: | 2019-07-21 | Release date: | 2020-02-05 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism. Nat.Struct.Mol.Biol., 27, 2020
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7TE5
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![BU of 7te5 by Molmil](/molmil-images/mine/7te5) | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK from Yersinia pestis | Descriptor: | MAGNESIUM ION, Pirin family protein Yhak | Authors: | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-01-04 | Release date: | 2022-01-12 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK from Yersinia pestis To Be Published
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1BS3
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![BU of 1bs3 by Molmil](/molmil-images/mine/1bs3) | P.SHERMANII SOD(FE+3) FLUORIDE | Descriptor: | FE (III) ION, FLUORIDE ION, SUPEROXIDE DISMUTASE | Authors: | Schmidt, M. | Deposit date: | 1998-08-31 | Release date: | 1999-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Manipulating the coordination mumber of the ferric iron within the cambialistic superoxide dismutase of Propionibacterium shermanii by changing the pH-value A crystallographic analysis Eur.J.Biochem., 262, 1999
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6NE8
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6WWZ
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![BU of 6wwz by Molmil](/molmil-images/mine/6wwz) | Cryo-EM structure of the human chemokine receptor CCR6 in complex with CCL20 and a Go protein | Descriptor: | C-C chemokine receptor type 6,C-C chemokine receptor type 6, C-C motif chemokine 20, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Wasilko, D.J, Johnson, Z.L, Ammirati, M, Han, S, Wu, H. | Deposit date: | 2020-05-09 | Release date: | 2020-06-24 | Last modified: | 2020-07-01 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20. Nat Commun, 11, 2020
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7TEM
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![BU of 7tem by Molmil](/molmil-images/mine/7tem) | Crystal Structure of the Putative Exported Protein YPO2471 from Yersinia pestis | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-01-05 | Release date: | 2022-01-19 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of the Putative Exported Protein YPO2471 from Yersinia pestis To Be Published
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3MUP
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![BU of 3mup by Molmil](/molmil-images/mine/3mup) | cIAP1-BIR3 domain in complex with the Smac-mimetic compound Smac037 | Descriptor: | (3S,6S,7R,9aS)-6-{[(2S)-2-aminobutanoyl]amino}-7-(2-aminoethyl)-N-(diphenylmethyl)-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | Authors: | Cossu, F, Malvezzi, F, Canevari, G, Milani, M. | Deposit date: | 2010-05-03 | Release date: | 2010-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Recognition of Smac-mimetic compounds by the BIR domain of cIAP1 Protein Sci., 19, 2010
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6PWV
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![BU of 6pwv by Molmil](/molmil-images/mine/6pwv) | Cryo-EM structure of MLL1 core complex bound to the nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | Deposit date: | 2019-07-23 | Release date: | 2019-12-18 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6WY3
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![BU of 6wy3 by Molmil](/molmil-images/mine/6wy3) | Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; P212121 form | Descriptor: | RNA (5'-R(*CP*CP*GP*GP*(LV2)P*GP*CP*CP*GP*G)-3') | Authors: | Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J. | Deposit date: | 2020-05-12 | Release date: | 2020-09-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.647 Å) | Cite: | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA. Nucleic Acids Res., 48, 2020
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6Q38
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![BU of 6q38 by Molmil](/molmil-images/mine/6q38) | The Crystal structure of CK2a bound to P1-C4 | Descriptor: | 3,5-bis(1-methyl-1,2,3-triazol-4-yl)benzoic acid, BENZOIC ACID, Casein kinase II subunit alpha, ... | Authors: | Brear, P, Iegre, J, Baker, D, Tan, Y, Sore, H, Donovan, D, Spring, D, Chandra, V, Hyvonen, M. | Deposit date: | 2018-12-03 | Release date: | 2019-04-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction. Chem Sci, 10, 2019
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6Q4Q
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![BU of 6q4q by Molmil](/molmil-images/mine/6q4q) | The Crystal structure of CK2a bound to P2-C4 | Descriptor: | 3,5-bis(1-methyl-1,2,3-triazol-4-yl)benzoic acid, ACETATE ION, BENZOIC ACID, ... | Authors: | Brear, P, Iegre, J, Baker, D, Tan, Y, Sore, H, Donovan, D, Spring, D, Chandra, V, Hyvonen, M. | Deposit date: | 2018-12-06 | Release date: | 2019-04-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Efficient development of stable and highly functionalised peptides targeting the CK2 alpha /CK2 beta protein-protein interaction. Chem Sci, 10, 2019
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7TFQ
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![BU of 7tfq by Molmil](/molmil-images/mine/7tfq) | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK Bound to Copper Ion from Yersinia pestis | Descriptor: | 1,2-ETHANEDIOL, COPPER (II) ION, FORMIC ACID, ... | Authors: | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2022-01-07 | Release date: | 2022-01-19 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK Bound to Copper Ion from Yersinia pestis To Be Published
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6WCJ
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![BU of 6wcj by Molmil](/molmil-images/mine/6wcj) | Asymmetric vertex of the clathrin minicoat cage | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | Authors: | Paraan, M, Mendez, J, Sharum, S, Kurtin, D, He, H, Stagg, S. | Deposit date: | 2020-03-30 | Release date: | 2020-08-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | The structures of natively assembled clathrin-coated vesicles. Sci Adv, 6, 2020
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6WZ9
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6X0U
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![BU of 6x0u by Molmil](/molmil-images/mine/6x0u) | Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge | Descriptor: | Gamma-tubulin complex component 3, Gamma-tubulin complex component 6, Mitotic-spindle organizing protein 1 | Authors: | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | Deposit date: | 2020-05-17 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
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1UYC
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![BU of 1uyc by Molmil](/molmil-images/mine/1uyc) | Human Hsp90-alpha with 9-Butyl-8-(2,5-dimethoxy-benzyl)-9H-purin-6-ylamine | Descriptor: | 9-BUTYL-8-(2,5-DIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE, HEAT SHOCK PROTEIN HSP 90-ALPHA | Authors: | Wright, L, Barril, X, Dymock, B, Sheridan, L, Surgenor, A, Beswick, M, Drysdale, M, Collier, A, Massey, A, Davies, N, Fink, A, Fromont, C, Aherne, W, Boxall, K, Sharp, S, Workman, P, Hubbard, R.E. | Deposit date: | 2004-03-02 | Release date: | 2004-07-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms Chem.Biol., 11, 2004
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6IBH
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![BU of 6ibh by Molmil](/molmil-images/mine/6ibh) | Copper binding protein from Laetisaria arvalis (LaX325) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity CAZyme, COPPER (II) ION, ... | Authors: | Frandsen, K.E.H, Tandrup, T, Labourel, A, Haon, M, Berrin, J.-G, Lo Leggio, L. | Deposit date: | 2018-11-30 | Release date: | 2019-11-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | A fungal family of lytic polysaccharide monooxygenase-like copper proteins. Nat.Chem.Biol., 16, 2020
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1BSM
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![BU of 1bsm by Molmil](/molmil-images/mine/1bsm) | P.SHERMANII SOD(FE+3) 140K PH8 | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE | Authors: | Schmidt, M. | Deposit date: | 1998-08-28 | Release date: | 1999-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Manipulating the coordination mumber of the ferric iron within the cambialistic superoxide dismutase of Propionibacterium shermanii by changing the pH-value A crystallographic analysis Eur.J.Biochem., 262, 1999
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