6WWZ
Cryo-EM structure of the human chemokine receptor CCR6 in complex with CCL20 and a Go protein
Summary for 6WWZ
Entry DOI | 10.2210/pdb6wwz/pdb |
EMDB information | 21950 |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, C-C motif chemokine 20, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, chemokine, chemokine receptor, complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 173507.66 |
Authors | Wasilko, D.J.,Johnson, Z.L.,Ammirati, M.,Han, S.,Wu, H. (deposition date: 2020-05-09, release date: 2020-06-24, Last modification date: 2020-07-01) |
Primary citation | Wasilko, D.J.,Johnson, Z.L.,Ammirati, M.,Che, Y.,Griffor, M.C.,Han, S.,Wu, H. Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20. Nat Commun, 11:3031-3031, 2020 Cited by PubMed: 32541785DOI: 10.1038/s41467-020-16820-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
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