7BFD
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7BFE
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7BFG
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2J7K
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3O0Q
| Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosine | 分子名称: | ADENOSINE, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | 登録日 | 2010-07-19 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
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3O0O
| Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP, GDP and Adenosylcobalamin | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | 登録日 | 2010-07-19 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
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3O0N
| Thermotoga maritima Ribonucleotide Reductase, NrdJ, in complex with dTTP and Adenosylcobalamin | 分子名称: | 5'-DEOXYADENOSINE, CHLORIDE ION, COBALAMIN, ... | 著者 | Larsson, K.-M, Logan, D.T, Nordlund, P. | 登録日 | 2010-07-19 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases. Acs Chem.Biol., 5, 2010
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6EXY
| Neutron crystal structure of perdeuterated galectin-3C in complex with glycerol | 分子名称: | GLYCEROL, Galectin-3 | 著者 | Manzoni, F, Schrader, T.E, Ostermann, A, Oksanen, E, Logan, D.T. | 登録日 | 2017-11-10 | 公開日 | 2018-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61, 2018
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6EYM
| Neutron crystal structure of perdeuterated galectin-3C in complex with lactose | 分子名称: | Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Manzoni, F, Coates, L, Blakeley, M.P, Oksanen, E, Logan, D.T. | 登録日 | 2017-11-13 | 公開日 | 2018-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61, 2018
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6F2Q
| Neutron crystal structure of perdeuterated galectin-3C in the ligand-free form | 分子名称: | Galectin-3 | 著者 | Manzoni, F, Blakeley, M.P, Oksanen, E, Logan, D.T. | 登録日 | 2017-11-27 | 公開日 | 2018-05-02 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.03 Å), X-RAY DIFFRACTION | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61, 2018
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4ZXO
| The structure of a GH26 beta-mannanase from Bacteroides ovatus, BoMan26A. | 分子名称: | Glycosyl hydrolase family 26, PHOSPHATE ION, POTASSIUM ION | 著者 | Bagenholm, V, Aurelius, O, Logan, D.T, Bouraoui, H, Stalbrand, H. | 登録日 | 2015-05-20 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus of Bacteroides ovatus: ENZYME SYNERGY AND CRYSTAL STRUCTURE OF A beta-MANNANASE. J. Biol. Chem., 292, 2017
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5A7C
| Crystal structure of the second bromodomain of human BRD3 in complex with compound | 分子名称: | 1,2-ETHANEDIOL, BROMODOMAIN-CONTAINING PROTEIN 3, N-(6-ACETAMIDOHEXYL)ACETAMIDE | 著者 | Welin, M, Kimbung, R, Diehl, C, Hakansson, M, Logan, D.T, Walse, B. | 登録日 | 2015-07-03 | 公開日 | 2016-03-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits Bet Bromodomain Proteins. Cancer Res., 76, 2016
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3HFF
| Monomeric human Cu,Zn Superoxide dismutase without Zn ligands | 分子名称: | Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Saraboji, K, Nordlund, A, Leinartait, L, Oliveberg, M, Logan, D.T. | 登録日 | 2009-05-11 | 公開日 | 2009-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional features cause misfolding of the ALS-provoking enzyme SOD1. Proc.Natl.Acad.Sci.USA, 106, 2009
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2XJL
| Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T. | 登録日 | 2010-07-07 | 公開日 | 2010-09-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1. J.Am.Chem.Soc., 132, 2010
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2XJK
| Monomeric Human Cu,Zn Superoxide dismutase | 分子名称: | COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | 著者 | Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T. | 登録日 | 2010-07-07 | 公開日 | 2010-09-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1. J.Am.Chem.Soc., 132, 2010
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8P23
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/CTP-bound state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, CYTIDINE-5'-TRIPHOSPHATE, ... | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-14 | 公開日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site Elife, 2023
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8P27
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dATP-bound state | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site Elife, 2023
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8P28
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric, dATP-bound state | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site To Be Published
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8P2D
| Cryo-EM structure of the dimeric form of the anaerobic ribonucleotide reductase from Prevotella copri produced in the presence of dATP and CTP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
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8P2C
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric state produced in the presence of dATP and CTP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | 著者 | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-15 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
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8P2S
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/dTTP/GTP-bound state | 分子名称: | Anaerobic ribonucleoside-triphosphate reductase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Bimai, O, Banerjee, I, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-16 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
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8P39
| Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dGTP/ATP-bound state | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, ... | 著者 | Bimai, O, Banerjee, I, Sjoberg, B.M, Logan, D.T. | 登録日 | 2023-05-17 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site To be published
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8PFF
| Galectin-3C in complex with a triazolesulfone derivative | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-(phenylsulfonyl)-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-oxane-3,4,5-triol, Galectin-3, MAGNESIUM ION, ... | 著者 | Kumar, R, Mahanti, M, Nilsson, U.J, Logan, D.T. | 登録日 | 2023-06-15 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds. J.Med.Chem., 66, 2023
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8PF9
| Galectin-3C in complex with a triazolesulfane derivative | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[oxidanyl(phenyl)-$l^{3}-sulfanyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-oxane-3,4,5-triol, Galectin-3, MAGNESIUM ION, ... | 著者 | Kumar, R, Mahanti, M, Nilsson, U.J, Logan, D.T. | 登録日 | 2023-06-15 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds. J.Med.Chem., 66, 2023
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1HK8
| STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE, MANGANESE (II) ION, ... | 著者 | Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T. | 登録日 | 2003-03-06 | 公開日 | 2003-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A Metal-Binding Site in the Catalytic Subunit of Anaerobic Ribonucleotide Reductase. Proc.Natl.Acad.Sci.USA, 100, 2003
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