8P2C

Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its tetrameric state produced in the presence of dATP and CTP

Summary for 8P2C

Entry DOI	10.2210/pdb8p2c/pdb
Related	8P23 8P27 8P28 8P2D 8P2S 8P39
EMDB information	17357 17358 17359 17360 17361 17373 17385
Descriptor	Anaerobic ribonucleoside-triphosphate reductase, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	ribonucleotide reductase glycyl radical enzyme allosteric regulation nucleotide biosynthesis, oxidoreductase, biosynthetic protein
Biological source	Segatella copri
Total number of polymer chains	4
Total formula weight	344535.62
Authors	Banerjee, I.,Bimai, O.,Sjoberg, B.M.,Logan, D.T. (deposition date: 2023-05-15, release date: 2023-09-13)
Primary citation	Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T. Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
Experimental method	ELECTRON MICROSCOPY (2.59 Å)

Structure validation