8P2S

Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/dTTP/GTP-bound state

Summary for 8P2S

• Entry DOI: 10.2210/pdb8p2s/pdb
• Related: 8P23 8P27 8P28 8P2C 8P2D 8P39
• EMDB information: 17357 17358 17359 17360 17361 17373 17385
• Descriptor: Anaerobic ribonucleoside-triphosphate reductase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ribonucleotide reductase glycyl radical enzyme allosteric regulation nucleotide biosynthesis, biosynthetic protein
• Biological source: Segatella copri
• Total number of polymer chains: 2
• Total formula weight: 170873.64

Authors

Bimai, O.,Banerjee, I.,Sjoberg, B.M.,Logan, D.T. (deposition date: 2023-05-16, release date: 2023-09-13)

• Primary citation: Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T.; Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site; eLife, 2023

Experimental method

ELECTRON MICROSCOPY (2.4 Å)