8P39

Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dGTP/ATP-bound state

Summary for 8P39

• Entry DOI: 10.2210/pdb8p39/pdb
• Related: 8P23 8P26 8P27 8P28 8P2D 8P2S
• EMDB information: 17357 17358 17359 17360 17361 17373 17385
• Descriptor: Anaerobic ribonucleoside-triphosphate reductase, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ribonucleotide reductase, glycyl radical enzyme, allosteric regulation, nucleotide biosynthesis, oxidoreductase, biosynthetic protein
• Biological source: Segatella copri
• Total number of polymer chains: 2
• Total formula weight: 170907.67

Authors

Bimai, O.,Banerjee, I.,Sjoberg, B.M.,Logan, D.T. (deposition date: 2023-05-17, release date: 2023-09-13)

• Primary citation: Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T.; Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site; To be published,

Experimental method

ELECTRON MICROSCOPY (2.58 Å)