8P23

Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/CTP-bound state

Summary for 8P23

• Entry DOI: 10.2210/pdb8p23/pdb
• Related: 8P27 8P28 8P2C 8P2D 8P2S 8P39
• EMDB information: 17357 17358 17359 17360 17361 17373 17385
• Descriptor: Anaerobic ribonucleoside-triphosphate reductase, ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: ribonucleotide reductase glycyl radical enzyme allosteric regulation nucleotide biosynthesis, biosynthetic protein
• Biological source: Prevotella copri
• Total number of polymer chains: 2
• Total formula weight: 171849.40

Authors

Banerjee, I.,Bimai, O.,Sjoberg, B.M.,Logan, D.T. (deposition date: 2023-05-14, release date: 2023-08-30)

• Primary citation: Bimai, O.,Banerjee, I.,Rozman Grinberg, I.,Huang, P.,Lundin, D.,Sjoberg, B.M.,Logan, D.T.; Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site; Elife, 2023; DOI: 10.7554/eLife.89292.1

Experimental method

ELECTRON MICROSCOPY (3.17 Å)