6X6D
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5MV2
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![BU of 5mv2 by Molmil](/molmil-images/mine/5mv2) | Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus | Descriptor: | E protein | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | Deposit date: | 2017-01-14 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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5MV1
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![BU of 5mv1 by Molmil](/molmil-images/mine/5mv1) | Crystal structure of the E protein of the Japanese encephalitis virulent virus | Descriptor: | E protein | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | Deposit date: | 2017-01-14 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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6OBA
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![BU of 6oba by Molmil](/molmil-images/mine/6oba) | The beta2 adrenergic receptor bound to a negative allosteric modulator | Descriptor: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, 6-bromo-N~2~-phenylquinazoline-2,4-diamine, Beta-2 adrenergic receptor,Lysozyme,Beta-2 adrenergic receptor, ... | Authors: | Liu, X, Stobel, A, Kaindl, J, Dengler, D, ClarK, M, Mahoney, J, Korczynska, M, Matt, R.A, Hubner, H, Xu, X, Stanek, M, Hirata, K, Shoichet, B, Sunahara, R, Gmeiner, R, Kobilka, B.K. | Deposit date: | 2019-03-20 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | An allosteric modulator binds to a conformational hub in the beta2adrenergic receptor. Nat.Chem.Biol., 16, 2020
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8XJ4
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![BU of 8xj4 by Molmil](/molmil-images/mine/8xj4) | Structure of prostatic acid phosphatase in human semen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prostatic acid phosphatase, alpha-D-mannopyranose, ... | Authors: | Liu, X.Z, Li, J.L, Deng, D, Wang, X. | Deposit date: | 2023-12-20 | Release date: | 2024-02-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Purification, identification and Cryo-EM structure of prostatic acid phosphatase in human semen. Biochem.Biophys.Res.Commun., 702, 2024
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8Z38
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![BU of 8z38 by Molmil](/molmil-images/mine/8z38) | FK506 binding protein 1B (including FK506) | Descriptor: | 6-CARBOXYPIPERIDINE, peptidylprolyl isomerase | Authors: | Liu, X.H, Zhao, W.H. | Deposit date: | 2024-04-14 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | High-resolution cocrystallized crystal structures of FK506 and FK506-binding proteins To Be Published
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8Z28
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![BU of 8z28 by Molmil](/molmil-images/mine/8z28) | FK506-binding protein 1B | Descriptor: | peptidylprolyl isomerase | Authors: | Liu, X.H, Zhao, W.H. | Deposit date: | 2024-04-12 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | FK506-binding protein 1B To Be Published
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6M19
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![BU of 6m19 by Molmil](/molmil-images/mine/6m19) | Template lasso peptide C24 mutant W14F | Descriptor: | lasso peptide | Authors: | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | Deposit date: | 2020-02-25 | Release date: | 2021-03-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
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8Z1R
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![BU of 8z1r by Molmil](/molmil-images/mine/8z1r) | isocitrate lyase MoMcl1 | Descriptor: | 1,2-ETHANEDIOL, Isocitrate lyase, MAGNESIUM ION | Authors: | Liu, X.H, Zhao, W.H. | Deposit date: | 2024-04-11 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | High-resolution crystal structure of the MoMcl1 protein To Be Published
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6EXV
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![BU of 6exv by Molmil](/molmil-images/mine/6exv) | Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin | Descriptor: | AMATOXIN, DNA (25-MER), DNA (36-MER), ... | Authors: | Liu, X, Farnung, L, Wigge, C, Cramer, P. | Deposit date: | 2017-11-09 | Release date: | 2018-03-21 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin. J. Biol. Chem., 293, 2018
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6AE9
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![BU of 6ae9 by Molmil](/molmil-images/mine/6ae9) | X-ray structure of the photosystem II phosphatase PBCP | Descriptor: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Liu, X.Y, Chai, J.C, Ou, X.M, Liu, Z.F. | Deposit date: | 2018-08-03 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural Insights into Substrate Selectivity, Catalytic Mechanism, and Redox Regulation of Rice Photosystem II Core Phosphatase. Mol Plant, 12, 2019
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6W9L
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![BU of 6w9l by Molmil](/molmil-images/mine/6w9l) | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with deacetylated deflazacort and PGC1a coregulator fragment | Descriptor: | (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one, GLYCEROL, Glucocorticoid Receptor, ... | Authors: | Liu, X, Ortlund, E.A. | Deposit date: | 2020-03-23 | Release date: | 2020-11-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. Proc.Natl.Acad.Sci.USA, 117, 2020
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6W9K
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4YR8
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![BU of 4yr8 by Molmil](/molmil-images/mine/4yr8) | Crystal structure of JNK in complex with a regulator protein | Descriptor: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | Authors: | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2015-03-14 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7, 2016
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1PQ0
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![BU of 1pq0 by Molmil](/molmil-images/mine/1pq0) | Crystal structure of mouse Bcl-xl | Descriptor: | Apoptosis regulator Bcl-X | Authors: | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | Deposit date: | 2003-06-17 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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1PQ1
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![BU of 1pq1 by Molmil](/molmil-images/mine/1pq1) | Crystal structure of Bcl-xl/Bim | Descriptor: | Apoptosis regulator Bcl-X, BCL2-like protein 11 | Authors: | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | Deposit date: | 2003-06-17 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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1LNU
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![BU of 1lnu by Molmil](/molmil-images/mine/1lnu) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A beta chain, ... | Authors: | Liu, X, Dai, S, Crawford, F, Fruge, R, Marrack, P, Kappler, J. | Deposit date: | 2002-05-03 | Release date: | 2002-08-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc.Natl.Acad.Sci.USA, 99, 2002
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6W9M
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4Q2E
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![BU of 4q2e by Molmil](/molmil-images/mine/4q2e) | CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S258C, active mutant) | Descriptor: | MAGNESIUM ION, MERCURY (II) ION, POTASSIUM ION, ... | Authors: | Liu, X, Yin, Y, Wu, J, Liu, Z. | Deposit date: | 2014-04-08 | Release date: | 2014-07-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis Nat Commun, 5, 2014
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4Q2G
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![BU of 4q2g by Molmil](/molmil-images/mine/4q2g) | CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant) | Descriptor: | MAGNESIUM ION, MERCURY (II) ION, Phosphatidate cytidylyltransferase, ... | Authors: | Liu, X, Yin, Y, Wu, J, Liu, Z. | Deposit date: | 2014-04-08 | Release date: | 2014-07-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis Nat Commun, 5, 2014
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8DQL
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![BU of 8dql by Molmil](/molmil-images/mine/8dql) | CryoEM structure of IglD | Descriptor: | Secretion system protein | Authors: | Liu, X, Clemens, D, Lee, B, Yang, X, Zhou, H, Horwitz, M. | Deposit date: | 2022-07-19 | Release date: | 2022-08-17 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System. Mbio, 13, 2022
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8DN2
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8DN4
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![BU of 8dn4 by Molmil](/molmil-images/mine/8dn4) | Cryo-EM structure of human Glycine Receptor alpha-1 beta heteromer, glycine-bound state3(desensitized state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-1, Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta, ... | Authors: | Liu, X, Wang, W. | Deposit date: | 2022-07-10 | Release date: | 2023-10-11 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Asymmetric gating of a human hetero-pentameric glycine receptor. Nat Commun, 14, 2023
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8DN5
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8DN3
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![BU of 8dn3 by Molmil](/molmil-images/mine/8dn3) | |