4Q2G

CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant)

Summary for 4Q2G

Related4Q2E
DescriptorPhosphatidate cytidylyltransferase, MERCURY (II) ION, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsintramembrane enzyme, cdsa fold, phospholipid biosynthesis lipid metabolism, ctp and phosphatidic acid binding, nucleotidyltransferase, membrane, transferase
Biological sourceThermotoga maritima MSB8
Cellular locationCell membrane; Multi-pass membrane protein (By similarity) Q9X1B7
Total number of polymer chains2
Total molecular weight66117.56
Authors
Liu, X.,Yin, Y.,Wu, J.,Liu, Z. (deposition date: 2014-04-08, release date: 2014-07-02, Last modification date: 2014-07-30)
Primary citation
Liu, X.,Yin, Y.,Wu, J.,Liu, Z.
Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis
Nat Commun, 5:4244-4244, 2014
PubMed: 24968740 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms5244
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.321203.2%3.9%7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4q2g
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Molmil generated image of 4q2g
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Molmil generated image of 4q2g
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