4Q2G
CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidate cytidylyltransferase | polymer | 290 | 32326.9 | 2 | UniProt (Q9X1B7) Pfam (PF01148) | Thermotoga maritima MSB8 | CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase |
| 2 | C, D, G, H (A, B) | MERCURY (II) ION | non-polymer | 200.6 | 4 | Chemie (HG) PubChem (26623) | |||
| 3 | E, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | F, J (A, B) | nonyl beta-D-glucopyranoside | non-polymer | 306.4 | 2 | Chemie (BNG) PubChem (57484544) PubChem (67410050) PubChem (67410054) PubChem (67410579) PubChem (67410580) PubChem (67410693) PubChem (67411265) PubChem (67411760) PubChem (67412070) PubChem (67412159) PubChem (67412975) PubChem (67413017) PubChem (71245600) PubChem (92471074) PubChem (92471075) PubChem (94290254) PubChem (94290256) PubChem (95566082) PubChem (95566083) PubChem (101527253) PubChem (113558) PubChem (155448) PubChem (9818005) PubChem (11415532) PubChem (129854788) PubChem (12986435) PubChem (131676744) PubChem (14656373) PubChem (136212546) |
Sequence modifications
A, B: 21 - 290 (UniProt: Q9X1B7)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Val 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Arg 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
| Cys 220 | Ser 200 | engineered mutation |
| Cys 278 | Ser 258 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64653.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1463.8 | |
| All* | Total formula weight | 66117.6 |
