6M19

Template lasso peptide C24 mutant W14F

Summary for 6M19

• Entry DOI: 10.2210/pdb6m19/pdb
• Descriptor: lasso peptide (1 entity in total)
• Functional Keywords: heterologous expression, site-direct mutagenesis, antibiotic
• Biological source: Streptomyces sp.
• Total number of polymer chains: 1
• Total formula weight: 1675.92

Authors

Liu, X.H.,Liu, T.,Ma, X.J.,Yu, J.H.,Yang, D.H.,Ma, M. (deposition date: 2020-02-25, release date: 2021-03-03, Last modification date: 2023-06-14)

• Primary citation: Liu, T.,Ma, X.,Yu, J.,Yang, W.,Wang, G.,Wang, Z.,Ge, Y.,Song, J.,Han, H.,Zhang, W.,Yang, D.,Liu, X.,Ma, M.; Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.; Chem Sci, 12:12353-12364, 2021; PubMed: 34603665; DOI: 10.1039/d1sc02695j

Experimental method

SOLUTION NMR