8HPX
| |
8F1G
| Crystal structure of human WDR5 in complex with compound WM662 | 分子名称: | (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid, GLYCEROL, SULFATE ION, ... | 著者 | Liu, H. | 登録日 | 2022-11-05 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. Acs Chem.Biol., 18, 2023
|
|
7KN3
| Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ... | 著者 | Liu, H, Zhu, X, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago. Adv Sci, 9, 2022
|
|
7KN4
| |
8W89
| Cryo-EM structure of the PEA-bound TAAR1-Gs complex | 分子名称: | 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | 登録日 | 2023-09-01 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
|
|
8ELQ
| |
7LM8
| |
7LM9
| Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient | 分子名称: | 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2021-02-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe, 29, 2021
|
|
8ELO
| |
8ELP
| |
7JMX
| Crystal structure of a SARS-CoV-2 cross-neutralizing antibody COVA1-16 Fab | 分子名称: | ACETATE ION, COVA1-16 heavy chain, COVA1-16 light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-08-03 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53, 2020
|
|
7T5I
| Crystal Structure of Strictosidine Synthase in complex with R-IPA(2-(1H-indol-3-yl) propan-1-amine) | 分子名称: | (2R)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | 登録日 | 2021-12-12 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids to be published
|
|
7T5J
| Crystal Structure of Strictosidine Synthase in complex with S-IPA (2-(1H-indol-3-yl) propan-1-amine) | 分子名称: | (2S)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | 登録日 | 2021-12-12 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids to be published
|
|
8SIS
| |
7JMW
| Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with cross-neutralizing antibody COVA1-16 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-08-03 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity, 53, 2020
|
|
8SIT
| |
8A0S
| |
8A3A
| |
7KN5
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
|
|
7KN6
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
|
|
7KN7
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
|
|
5ET1
| Crystal structure of Myo3b-ARB1 in complex with Espin1-AR | 分子名称: | Espin, GLYCEROL, Myosin-IIIb | 著者 | Liu, H, Li, J, liu, W, Zhang, M. | 登録日 | 2015-11-17 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
|
|
7ZYI
| Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody | 分子名称: | CHOLESTEROL, GLYCOCHENODEOXYCHOLIC ACID, Nanobody, ... | 著者 | Liu, H, Irobalieva, R.N, Bang-Sorensen, R, Nosol, K, Mukherjee, S, Agrawal, P, Stieger, B, Kossiakoff, A.A, Locher, K.P. | 登録日 | 2022-05-24 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Res., 32, 2022
|
|
8A34
| MTH1 in complex with TH013071 | 分子名称: | 5-(2-phenylphenyl)-1H-pyrimidine-2,4-dione, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Liu, H, Scaletti, E, Stenmark, P. | 登録日 | 2022-06-07 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | MTH1 in complex with TH013071 To Be Published
|
|
1SOF
| Crystal structure of the azotobacter vinelandii bacterioferritin at 2.6 A resolution | 分子名称: | BARIUM ION, Bacterioferritin, FE (II) ION, ... | 著者 | Liu, H.L, Huang, J.F, Bi, R.C. | 登録日 | 2004-03-14 | 公開日 | 2005-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii Febs Lett., 573, 2004
|
|