8A0S

MTH1 in complex with TH013350

Summary for 8A0S

Entry DOI	10.2210/pdb8a0s/pdb
Descriptor	7,8-dihydro-8-oxoguanine triphosphatase, 4-[(2-chlorophenyl)methylsulfanyl]-5~{H}-pyrimidin-2-one, SULFATE ION, ... (4 entities in total)
Functional Keywords	inhibitor, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	18855.24
Authors	Liu, H.,Scaletti, E.,Stenmark, P. (deposition date: 2022-05-30, release date: 2023-09-20)
Primary citation	Liu, H.,Scaletti, E.,Stenmark, P. MTH1 in complex with TH013350 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation