1QU5
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3MOB
| Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced Fab) with 11 aa gp41 MPER-derived peptide | Descriptor: | ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, gp41 MPER-derived peptide | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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3MOA
| Crystal structure of the neutralizing HIV antibody 2F5 Fab fragment (recombinantly produced Fab) with 17 aa gp41 MPER-derived peptide | Descriptor: | ANTI-HIV-1 ANTIBODY 2F5 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 2F5 LIGHT CHAIN, gp41 MPER-derived peptide | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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4RIS
| Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk | Descriptor: | CH58-UA Fab heavy chain, CH58-UA Fab light chain, Envelope glycoprotein | Authors: | Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. | Deposit date: | 2014-10-07 | Release date: | 2015-08-12 | Last modified: | 2015-09-02 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
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4RIR
| Structural Analysis of the Unmutated Ancestor of the HIV-1 Envelope V2 Region Antibody CH58 Isolated From an RV144 HIV-1 Vaccine Efficacy Trial Vaccinee and Associated with Decreased Transmission Risk | Descriptor: | CH58-UA Fab heavy chain, CH58-UA Fab light chain | Authors: | Nicely, N.I, Wiehe, K, Kepler, T.B, Jaeger, F.H, Dennison, S.M, Liao, H.-X, Alam, S.M, Hwang, K.-K, Bonsignori, M, Rerks-Ngarm, S, Nitayaphan, S, Pitisuttithum, P, Kaewkungwal, J, Robb, M.L, O'Connell, R.J, Michael, N.L, Kim, J.H, Haynes, B.F. | Deposit date: | 2014-10-07 | Release date: | 2015-08-12 | Last modified: | 2015-09-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee. EBioMedicine, 2, 2015
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3MNZ
| Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide bearing Ala substitutions in a helical conformation | Descriptor: | ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, SODIUM ION, ... | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies To be Published
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1YQJ
| Crystal Structure of p38 Alpha in Complex with a Selective Pyridazine Inhibitor | Descriptor: | 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE, Mitogen-activated protein kinase 14, SULFATE ION | Authors: | Tamayo, N, Liao, H, Goldberg, M, Syed, R, Li, V, Powers, D, Tudor, Y, Yu, V, Wong, M.L, Henkle, B, Middelton, S, Harvey, T, Jang, G, Hungate, R, Dominguez, C. | Deposit date: | 2005-02-01 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 15, 2005
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1FHQ
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1FHR
| SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE | Descriptor: | DNA REPAIR PROTEIN RAD9, PROTEIN KINASE SPK1 | Authors: | Byeon, I.-J.L, Liao, H, Yongkiettrakul, S, Tsai, M.-D. | Deposit date: | 2000-08-02 | Release date: | 2000-10-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. J.Mol.Biol., 302, 2000
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1A8Y
| CRYSTAL STRUCTURE OF CALSEQUESTRIN FROM RABBIT SKELETAL MUSCLE SARCOPLASMIC RETICULUM AT 2.4 A RESOLUTION | Descriptor: | CALSEQUESTRIN | Authors: | Wang, S, Trumble, W.R, Liao, H, Wesson, C.R, Dunker, A.K, Kang, C. | Deposit date: | 1998-03-31 | Release date: | 1999-03-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum. Nat.Struct.Biol., 5, 1998
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7CE2
| The Crystal structure of TeNT Hc complexed with neutralizing antibody | Descriptor: | Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain | Authors: | Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H. | Deposit date: | 2020-06-21 | Release date: | 2021-04-07 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural basis of tetanus toxin neutralization by native human monoclonal antibodies. Cell Rep, 35, 2021
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5DD0
| Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | Descriptor: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide | Authors: | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | Deposit date: | 2015-08-24 | Release date: | 2016-05-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.488 Å) | Cite: | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
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5DD1
| Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | Descriptor: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN | Authors: | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | Deposit date: | 2015-08-24 | Release date: | 2016-05-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.597 Å) | Cite: | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
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1G3G
| NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53 | Descriptor: | PROTEIN KINASE SPK1 | Authors: | Yuan, C, Liao, H, Su, M, Yongkiettrakul, S, Byeon, I.-J.L, Tsai, M.-D. | Deposit date: | 2000-10-24 | Release date: | 2001-01-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9 J.Mol.Biol., 304, 2000
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5EA0
| Structure of the antibody 7968 with human complement factor H-derived peptide | Descriptor: | Complement factor H-related protein 2, Heavy chain of antibody 7968 Fab fragment, Light chain of antibody 7968 Fab fragment | Authors: | Bushey, R.T, Moody, M.A, Nicely, N.I, Alam, S.M, Haynes, B.F, Winkler, M.T, Gottlin, E.B, Campa, M.J, Liao, H.-X, Patz Jr, E.F. | Deposit date: | 2015-10-15 | Release date: | 2016-05-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Therapeutic Antibody for Cancer, Derived from Single Human B Cells. Cell Rep, 15, 2016
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7XB0
| Crystal structure of Omicron BA.2 RBD complexed with hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, L, Liao, H, Meng, Y, Li, W. | Deposit date: | 2022-03-19 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185, 2022
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7XB1
| Crystal structure of Omicron BA.3 RBD complexed with hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, W, Meng, Y, Liao, H. | Deposit date: | 2022-03-19 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185, 2022
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