8Y3W
| The Cryo-EM structure of anti-phage defense associated DSR2 tetramer bound with two DSAD1 inhibitors (same side) | Descriptor: | DSR anti-defence 1, SIR2-like domain-containing protein | Authors: | Wang, R.W, Xu, Q, Wu, Z.X, Li, J.L, Shi, Z.B, Li, F.X. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15, 2024
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8YKX
| Cryo-EM structure of succinate receptor SUCR1 bound to maleic acid | Descriptor: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | Deposit date: | 2024-03-05 | Release date: | 2024-05-29 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 34, 2024
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8Y34
| Cryo-EM structure of anti-phage defense associated DSR2 (H171A) (map2) | Descriptor: | SIR2-like domain-containing protein | Authors: | Wang, R.W, Xu, Q, Wu, Z.X, Li, J.L, Shi, Z.B, Li, F.X. | Deposit date: | 2024-01-28 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15, 2024
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8Y3M
| Cryo-EM structure of DSR2-DSAD1 complex (cross-linked) | Descriptor: | DSR anti-defence 1, SIR2-like domain-containing protein | Authors: | Wang, R.W, Xu, Q, Wu, Z.X, Li, J.L, Shi, Z.B, Li, F.X. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15, 2024
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8Y3Y
| The Cryo-EM structure of anti-phage defense associated DSR2 tetramer bound with two DSAD1 inhibitors (opposite side) | Descriptor: | DSR anti-defence 1, SIR2-like domain-containing protein | Authors: | Wang, R.W, Xu, Q, Wu, Z.X, Li, J.L, Shi, Z.B, Li, F.X. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15, 2024
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8ZMV
| Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-24 | Release date: | 2024-07-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec To Be Published
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8YKW
| Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | Descriptor: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | Deposit date: | 2024-03-05 | Release date: | 2024-05-29 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 34, 2024
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9J23
| Structure of a triple-helix region of human Collagen type II from Trautec | Descriptor: | Triple-helix region of human collagen type II | Authors: | Fan, X, Zhai, Y, Chu, Y, Fu, S, Li, D, Feng, P, Cao, K, Li, J, Si, Y, Ma, L, Qian, S. | Deposit date: | 2024-08-06 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a triple-helix region of human Collagen type II from Trautec To Be Published
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7X8L
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7EGH
| TFIID lobe C subcomplex | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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5DP4
| Crystal Structure of EV71 3C Proteinase in complex with compound 3 | Descriptor: | 3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP5
| Crystal Structure of EV71 3C Proteinase in complex with compound 4 | Descriptor: | 3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2016-04-06 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP7
| Crystal Structure of EV71 3C Proteinase in complex with compound 5 | Descriptor: | 3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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8W7J
| Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC with chain A bounded to substrate PneA and GTP. | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, PneA LP, ... | Authors: | Li, Y, Luo, M, Shao, K, Li, J, Li, Z. | Deposit date: | 2023-08-30 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers. Nat Commun, 15, 2024
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5U2U
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6VHH
| Human Teneurin-2 and human Latrophilin-3 binary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor L3, ... | Authors: | Xie, Y, Li, J, Arac, D, Zhao, M. | Deposit date: | 2020-01-09 | Release date: | 2020-06-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism. Nat Commun, 11, 2020
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5SV7
| The Crystal structure of a chaperone | Descriptor: | Eukaryotic translation initiation factor 2-alpha kinase 3 | Authors: | Wang, P, Li, J, Sha, B. | Deposit date: | 2016-08-04 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.209 Å) | Cite: | The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins. Acta Crystallogr D Struct Biol, 72, 2016
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5U2L
| Crystal structure of the Hsp104 N-terminal domain from Candida albicans | Descriptor: | Heat shock protein 104 | Authors: | Wang, P, Li, J, Sha, B. | Deposit date: | 2016-11-30 | Release date: | 2017-04-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6555 Å) | Cite: | Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions. Acta Crystallogr D Struct Biol, 73, 2017
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6JD5
| ATPase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein, MAGNESIUM ION | Authors: | Wang, S.H, Li, J, Rao, Z.H. | Deposit date: | 2019-01-31 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into substrate recognition by the type VII secretion system. Protein Cell, 11, 2020
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6J18
| ATPase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ESX-5 secretion system protein EccC5, MAGNESIUM ION | Authors: | Wang, S.H, Li, J, Rao, Z.H. | Deposit date: | 2018-12-28 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into substrate recognition by the type VII secretion system. Protein Cell, 11, 2020
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6J19
| ATPase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ESAT-6-like protein EsxB, ESX-1 secretion system protein EccCb1, ... | Authors: | Wang, S.H, Li, J, Rao, Z.H. | Deposit date: | 2018-12-28 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.978 Å) | Cite: | Structural insights into substrate recognition by the type VII secretion system. Protein Cell, 11, 2020
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5DP3
| Crystal Structure of EV71 3C Proteinase in complex with compound 2 | Descriptor: | 3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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6J17
| ATPase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ESX-3 secretion system protein EccC3, MAGNESIUM ION | Authors: | Wang, S.H, Li, J, Rao, Z.H. | Deposit date: | 2018-12-28 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.975 Å) | Cite: | Structural insights into substrate recognition by the type VII secretion system. Protein Cell, 11, 2020
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5DP6
| Crystal Structure of EV71 3C Proteinase in complex with compound 7 | Descriptor: | 3C proteinase, ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | Authors: | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | Deposit date: | 2015-09-12 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5TPV
| X-ray structure of WlaRA (TDP-fucose-3,4-ketoisomerase) from Campylobacter jejuni | Descriptor: | PHOSPHATE ION, THYMIDINE-5'-DIPHOSPHATE, WlaRA, ... | Authors: | Holden, H.M, Thoden, J.B, Li, Z.A, Riegert, A.S, Goneau, M.-F, Cunningham, A.M, Vinograd, E, Schoenhofen, I.C, Gilbert, M, Li, J. | Deposit date: | 2016-10-21 | Release date: | 2017-02-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116. Glycobiology, 27, 2017
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