5SV7
The Crystal structure of a chaperone
Summary for 5SV7
Entry DOI | 10.2210/pdb5sv7/pdb |
Descriptor | Eukaryotic translation initiation factor 2-alpha kinase 3 (2 entities in total) |
Functional Keywords | chaperone, translation |
Biological source | Homo sapiens (Human) |
Cellular location | Endoplasmic reticulum membrane; Single-pass type I membrane protein: Q9NZJ5 |
Total number of polymer chains | 4 |
Total formula weight | 146099.11 |
Authors | |
Primary citation | Wang, P.,Li, J.,Sha, B. The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins. Acta Crystallogr D Struct Biol, 72:1290-1297, 2016 Cited by PubMed: 27917829DOI: 10.1107/S2059798316018064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.209 Å) |
Structure validation
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