8Y3Y
The Cryo-EM structure of anti-phage defense associated DSR2 tetramer bound with two DSAD1 inhibitors (opposite side)
Summary for 8Y3Y
Entry DOI | 10.2210/pdb8y3y/pdb |
EMDB information | 38907 |
Descriptor | SIR2-like domain-containing protein, DSR anti-defence 1 (2 entities in total) |
Functional Keywords | nadase, anti-phage defense, complex, immune evasion, immunosuppressant |
Biological source | Bacillus subtilis More |
Total number of polymer chains | 6 |
Total formula weight | 502289.02 |
Authors | |
Primary citation | Wang, R.,Xu, Q.,Wu, Z.,Li, J.,Guo, H.,Liao, T.,Shi, Y.,Yuan, L.,Gao, H.,Yang, R.,Shi, Z.,Li, F. The structural basis of the activation and inhibition of DSR2 NADase by phage proteins. Nat Commun, 15:6185-6185, 2024 Cited by PubMed: 39039073DOI: 10.1038/s41467-024-50410-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.33 Å) |
Structure validation
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