8TS0
 
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1N3B
 | | Crystal Structure of Dephosphocoenzyme A kinase from Escherichia coli | | 分子名称: | Dephospho-CoA kinase, SULFATE ION | | 著者 | O'Toole, N, Barbosa, J.A.R.G, Li, Y, Hung, L.-W, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2002-10-25 | | 公開日 | 2003-01-28 | | 最終更新日 | 2017-02-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of a Trimeric Form of Dephosphocoenzyme A Kinase from Escherichia coli
Protein Sci., 12, 2003
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1PS6
 | | Crystal structure of E.coli PdxA | | 分子名称: | 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | | 登録日 | 2003-06-20 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
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3JBL
 | | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization | | 分子名称: | NLR family CARD domain-containing protein 4 | | 著者 | Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. | | 登録日 | 2015-09-05 | | 公開日 | 2015-10-21 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
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2G1K
 | | Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimate at 1.75 angstrom resolution | | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, CHLORIDE ION, SULFATE ION, ... | | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | | 登録日 | 2006-02-14 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
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1PS7
 | | Crystal structure of E.coli PdxA | | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | | 登録日 | 2003-06-20 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
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4KQZ
 | | structure of the receptor binding domain (RBD) of MERS-CoV spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Bao, J, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-05-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.514 Å) | | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
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4NQJ
 | | Structure of coiled-coil domain | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | | 著者 | Yang, M, Li, Y. | | 登録日 | 2013-11-25 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | | 主引用文献 | Structural insights into the TRIM family of ubiquitin E3 ligases.
Cell Res., 24, 2014
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1T0F
 | | Crystal Structure of the TnsA/TnsC(504-555) complex | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MALONIC ACID, ... | | 著者 | Ronning, D.R, Li, Y, Perez, Z.N, Ross, P.D, Hickman, A.B, Craig, N.L, Dyda, F. | | 登録日 | 2004-04-08 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
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5CP7
 | | Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides | | 分子名称: | Heavy Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7, Light Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7 | | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | | 登録日 | 2015-07-21 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Anal. Chem., 91, 2019
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4KR0
 | | Complex structure of MERS-CoV spike RBD bound to CD26 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-05-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
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1PTM
 | | Crystal structure of E.coli PdxA | | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION | | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2003-06-23 | | 公開日 | 2003-11-04 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
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1Q18
 | | Crystal structure of E.coli glucokinase (Glk) | | 分子名称: | Glucokinase | | 著者 | Lunin, V.V, Li, Y, Schrag, J.D, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2003-07-18 | | 公開日 | 2004-07-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose.
J.Bacteriol., 186, 2004
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2G1J
 | | Crystal structure of Mycobacterium tuberculosis Shikimate Kinase at 2.0 angstrom resolution | | 分子名称: | SULFATE ION, Shikimate kinase | | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | | 登録日 | 2006-02-14 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
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1IJI
 | | Crystal Structure of L-Histidinol Phosphate Aminotransferase with PLP | | 分子名称: | Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Sivaraman, J, Li, Y, Larocque, R, Schrag, J.D, Cygler, M, Matte, A. | | 登録日 | 2001-04-26 | | 公開日 | 2001-08-29 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
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8F8E
 | | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound | | 分子名称: | (3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide, CITRIC ACID, DDB1- and CUL4-associated factor 1 | | 著者 | Kimani, S, Li, A, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2022-11-21 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound
To be published
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7THM
 | | SARS-CoV-2 nsp12/7/8 complex with a native N-terminus nsp9 | | 分子名称: | MANGANESE (II) ION, Non-structural protein 7, Non-structural protein 8, ... | | 著者 | Osinski, A, Tagliabracci, V.S, Chen, Z, Li, Y. | | 登録日 | 2022-01-11 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | The mechanism of RNA capping by SARS-CoV-2.
Nature, 609, 2022
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1KAE
 | | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR) | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Histidinol dehydrogenase, ... | | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | | 登録日 | 2001-11-01 | | 公開日 | 2002-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1KAH
 | | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR) | | 分子名称: | HISTIDINE, Histidinol dehydrogenase, ZINC ION | | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | | 登録日 | 2001-11-02 | | 公開日 | 2002-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1K75
 | | The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication. | | 分子名称: | GLYCEROL, L-histidinol dehydrogenase, SULFATE ION | | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2001-10-18 | | 公開日 | 2002-02-27 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JA3
 | | Crystal Structure of the Murine NK Cell Inhibitory Receptor Ly-49I | | 分子名称: | MHC class I recognition receptor Ly49I | | 著者 | Dimasi, N, Sawicki, W.M, Reineck, L.A, Li, Y, Natarajan, K, Murgulies, D.H, Mariuzza, A.R. | | 登録日 | 2001-05-29 | | 公開日 | 2002-07-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family.
J.Mol.Biol., 320, 2002
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1JHN
 | | Crystal Structure of the Lumenal Domain of Calnexin | | 分子名称: | CALCIUM ION, calnexin | | 著者 | Schrag, J.D, Bergeron, J.M, Li, Y, Borisova, S, Hahn, M, Thomas, D.Y, Cygler, M. | | 登録日 | 2001-06-28 | | 公開日 | 2001-10-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The Structure of calnexin, an ER chaperone involved in quality control of protein folding.
Mol.Cell, 8, 2001
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3O6F
 | | Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4 | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | | 著者 | Yin, Y, Li, Y, Martin, R, Mariuzza, R.A. | | 登録日 | 2010-07-29 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection.
Embo J., 30, 2011
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1FC4
 | | 2-AMINO-3-KETOBUTYRATE COA LIGASE | | 分子名称: | 2-AMINO-3-KETOBUTYRATE CONENZYME A LIGASE, 2-AMINO-3-KETOBUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Schmidt, A, Matte, A, Li, Y, Sivaraman, J, Larocque, R, Schrag, J.D, Smith, C, Sauve, V, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2000-07-17 | | 公開日 | 2001-05-02 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry, 40, 2001
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1KAR
 | | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR) | | 分子名称: | HISTAMINE, Histidinol dehydrogenase, ZINC ION | | 著者 | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | | 登録日 | 2001-11-02 | | 公開日 | 2002-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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