7THM

SARS-CoV-2 nsp12/7/8 complex with a native N-terminus nsp9

Summary for 7THM

Entry DOI	10.2210/pdb7thm/pdb
EMDB information	25898
Descriptor	RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (7 entities in total)
Functional Keywords	polymerase, niran, capping, nsp9, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More
Total number of polymer chains	5
Total formula weight	172588.76
Authors	Osinski, A.,Tagliabracci, V.S.,Chen, Z.,Li, Y. (deposition date: 2022-01-11, release date: 2022-03-16, Last modification date: 2024-01-17)
Primary citation	Park, G.J.,Osinski, A.,Hernandez, G.,Eitson, J.L.,Majumdar, A.,Tonelli, M.,Henzler-Wildman, K.,Pawlowski, K.,Chen, Z.,Li, Y.,Schoggins, J.W.,Tagliabracci, V.S. The mechanism of RNA capping by SARS-CoV-2. Nature, 609:793-800, 2022 Cited by PubMed: 35944563 DOI: 10.1038/s41586-022-05185-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.18 Å)

Structure validation