4JPB
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![BU of 4jpb by Molmil](/molmil-images/mine/4jpb) | The structure of a ternary complex between CheA domains P4 and P5 with CheW and with an unzipped fragment of TM14, a chemoreceptor analog from Thermotoga maritima. | Descriptor: | Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein | Authors: | Li, X, Bayas, C, Bilwes, A.M, Crane, B.R. | Deposit date: | 2013-03-19 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.186 Å) | Cite: | The 3.2 angstrom resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. Biochemistry, 52, 2013
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6A5M
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![BU of 6a5m by Molmil](/molmil-images/mine/6a5m) | Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 2 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2FLU
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![BU of 2flu by Molmil](/molmil-images/mine/2flu) | Crystal Structure of the Kelch-Neh2 Complex | Descriptor: | Kelch-like ECH-associated protein 1, Nrf2 | Authors: | Li, X, Lo, J, Beamer, L, Hannink, M. | Deposit date: | 2006-01-06 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling. Embo J., 25, 2006
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6A5N
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![BU of 6a5n by Molmil](/molmil-images/mine/6a5n) | Crystal structure of Arabidopsis thaliana SUVH6 in complex with methylated DNA | Descriptor: | DNA (5'-D(*CP*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A5K
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![BU of 6a5k by Molmil](/molmil-images/mine/6a5k) | Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... | Authors: | Li, X, Du, J. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4HYG
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![BU of 4hyg by Molmil](/molmil-images/mine/4hyg) | Structure of a presenilin family intramembrane aspartate protease in C222 space group | Descriptor: | Putative uncharacterized protein | Authors: | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | Deposit date: | 2012-11-13 | Release date: | 2012-12-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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4FWI
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![BU of 4fwi by Molmil](/molmil-images/mine/4fwi) | Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter | Descriptor: | ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Li, X, Ge, J, Yang, M, Wang, N. | Deposit date: | 2012-07-01 | Release date: | 2013-01-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.892 Å) | Cite: | Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain Acta Crystallogr.,Sect.D, 69, 2013
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3RQF
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![BU of 3rqf by Molmil](/molmil-images/mine/3rqf) | |
7EQH
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![BU of 7eqh by Molmil](/molmil-images/mine/7eqh) | |
7WW2
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![BU of 7ww2 by Molmil](/molmil-images/mine/7ww2) | Structure of an Isocytosine specific deaminase Vcz | Descriptor: | 8-oxoguanine deaminase, ZINC ION | Authors: | Li, X.J, Wu, B.X. | Deposit date: | 2022-02-12 | Release date: | 2023-02-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural characterization of an isocytosine-specific deaminase VCZ reveals its application potential in the anti-cancer therapy. Iscience, 26, 2023
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7CR2
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![BU of 7cr2 by Molmil](/molmil-images/mine/7cr2) | human KCNQ2 in complex with retigabine | Descriptor: | Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR7
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![BU of 7cr7 by Molmil](/molmil-images/mine/7cr7) | human KCNQ2-CaM in complex with retigabine | Descriptor: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR0
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![BU of 7cr0 by Molmil](/molmil-images/mine/7cr0) | human KCNQ2 in apo state | Descriptor: | Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR3
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![BU of 7cr3 by Molmil](/molmil-images/mine/7cr3) | human KCNQ2-CaM in apo state | Descriptor: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR4
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![BU of 7cr4 by Molmil](/molmil-images/mine/7cr4) | human KCNQ2-CaM in complex with ztz240 | Descriptor: | Calmodulin-3, N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CR1
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![BU of 7cr1 by Molmil](/molmil-images/mine/7cr1) | human KCNQ2 in complex with ztz240 | Descriptor: | N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | Deposit date: | 2020-08-12 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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3RQG
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![BU of 3rqg by Molmil](/molmil-images/mine/3rqg) | |
6KPC
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![BU of 6kpc by Molmil](/molmil-images/mine/6kpc) | Crystal structure of an agonist bound GPCR | Descriptor: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2,Endolysin | Authors: | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Wu, M, Liu, Z.J. | Deposit date: | 2019-08-15 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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4KMP
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![BU of 4kmp by Molmil](/molmil-images/mine/4kmp) | Structure of XIAP-BIR3 and inhibitor | Descriptor: | (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], E3 ubiquitin-protein ligase XIAP, ZINC ION | Authors: | Li, X, Wang, J, Condon, S.M, Shi, Y. | Deposit date: | 2013-05-08 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of XIAP-BIR3 and inhibitor To be Published
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3RQE
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![BU of 3rqe by Molmil](/molmil-images/mine/3rqe) | |
7JI2
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![BU of 7ji2 by Molmil](/molmil-images/mine/7ji2) | Crystal Structure of H2-Kb in complex with a OVA mutant peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | Authors: | Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J. | Deposit date: | 2020-07-22 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection. Science, 371, 2021
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3SIP
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![BU of 3sip by Molmil](/molmil-images/mine/3sip) | Crystal structure of drICE and dIAP1-BIR1 complex | Descriptor: | Apoptosis 1 inhibitor, Caspase, ZINC ION | Authors: | Li, X, Wang, J, Shi, Y. | Deposit date: | 2011-06-20 | Release date: | 2011-08-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.496 Å) | Cite: | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun, 2, 2011
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6KPF
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![BU of 6kpf by Molmil](/molmil-images/mine/6kpf) | Cryo-EM structure of a class A GPCR with G protein complex | Descriptor: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Shen, L, Wang, Y.X, Liu, Z.J. | Deposit date: | 2019-08-15 | Release date: | 2020-02-12 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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4KMN
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![BU of 4kmn by Molmil](/molmil-images/mine/4kmn) | Structure of cIAP1-BIR3 and inhibitor | Descriptor: | (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, Baculoviral IAP repeat-containing protein 2, PHOSPHATE ION, ... | Authors: | Li, X, Wang, J, Condon, S.M, Shi, Y. | Deposit date: | 2013-05-08 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.523 Å) | Cite: | Structure of cIAP1-BIR3 and inhibitor To be Published
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2DC2
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![BU of 2dc2 by Molmil](/molmil-images/mine/2dc2) | Solution Structure of PDZ Domain | Descriptor: | golgi associated PDZ and coiled-coil motif containing isoform b | Authors: | Li, X, Wu, J, Shi, Y. | Deposit date: | 2005-12-20 | Release date: | 2006-09-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin Protein Sci., 15, 2006
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