2FLU

Crystal Structure of the Kelch-Neh2 Complex

Summary for 2FLU

• Entry DOI: 10.2210/pdb2flu/pdb
• Related: 1U6D 1ZGK
• Descriptor: Kelch-like ECH-associated protein 1, Nrf2 (3 entities in total)
• Functional Keywords: kelch domain, protein-peptide complex, beta-propeller, ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytosol: Q16236
• Total number of polymer chains: 2
• Total formula weight: 35552.54

Authors

Li, X.,Lo, J.,Beamer, L.,Hannink, M. (deposition date: 2006-01-06, release date: 2006-08-15, Last modification date: 2023-08-30)

• Primary citation: Lo, S.C.,Li, X.,Henzl, M.T.,Beamer, L.J.,Hannink, M.; Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.; Embo J., 25:3605-3617, 2006; PubMed: 16888629; DOI: 10.1038/sj.emboj.7601243

Experimental method

X-RAY DIFFRACTION (1.5 Å)