3RQE

Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD1

Summary for 3RQE

Entry DOI	10.2210/pdb3rqe/pdb
Related	3AJM 3L8I 3L8J 3RQF 3RQG
Descriptor	Programmed cell death protein 10, Paxillin LD1 peptide (2 entities in total)
Functional Keywords	protein-peptide complex, protein binding, fat domain, dimerization, cerebral cavernous malformation
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q9BUL8
Total number of polymer chains	5
Total formula weight	101214.67
Authors	Li, X.,Zhang, R.,Boggon, T.J. (deposition date: 2011-04-28, release date: 2011-06-01, Last modification date: 2023-09-13)
Primary citation	Li, X.,Ji, W.,Zhang, R.,Folta-Stogniew, E.,Min, W.,Boggon, T.J. Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3). J.Biol.Chem., 286:26138-26147, 2011 Cited by PubMed: 21632544 DOI: 10.1074/jbc.M110.211250 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation