7CR2

human KCNQ2 in complex with retigabine

Summary for 7CR2

• Entry DOI: 10.2210/pdb7cr2/pdb
• Related: 7CR0 7CR1
• EMDB information: 30445
• Descriptor: Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate (2 entities in total)
• Functional Keywords: ion channel, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 295724.57

Authors

Li, X.,Lv, D.,Wang, J.,Ye, S.,Guo, J. (deposition date: 2020-08-12, release date: 2020-09-16, Last modification date: 2024-03-27)

• Primary citation: Li, X.,Zhang, Q.,Guo, P.,Fu, J.,Mei, L.,Lv, D.,Wang, J.,Lai, D.,Ye, S.,Yang, H.,Guo, J.; Molecular basis for ligand activation of the human KCNQ2 channel.; Cell Res., 31:52-61, 2021; PubMed: 32884139; DOI: 10.1038/s41422-020-00410-8

Experimental method

ELECTRON MICROSCOPY (3.2 Å)