7CR2
human KCNQ2 in complex with retigabine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Potassium voltage-gated channel subfamily KQT member 2 | polymer | 656 | 73627.8 | 4 | UniProt (O43526) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) Pfam (PF16642) In PDB | Homo sapiens (Human) | KQT-like 2,Neuroblastoma-specific potassium channel subunit alpha KvLQT2,Voltage-gated potassium channel subunit Kv7.2 |
2 | A, B, C, D | ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate | non-polymer | 303.3 | 4 | Chemie (FBX) |
Sequence modifications
A, B, C, D: 64 - 702 (UniProt: O43526)
PDB | External Database | Details |
---|---|---|
Met 63 | - | initiating methionine |
Val 703 | - | expression tag |
Glu 704 | - | expression tag |
Gly 705 | - | expression tag |
Gly 706 | - | expression tag |
Ser 707 | - | expression tag |
Ser 708 | - | expression tag |
Gly 709 | - | expression tag |
Gly 710 | - | expression tag |
Trp 711 | - | expression tag |
Ser 712 | - | expression tag |
His 713 | - | expression tag |
Pro 714 | - | expression tag |
Gln 715 | - | expression tag |
Phe 716 | - | expression tag |
Glu 717 | - | expression tag |
Lys 718 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 294511.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1213.3 | |
All* | Total formula weight | 295724.6 |