1NBF
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | 分子名称: | Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y. | 登録日 | 2002-12-02 | 公開日 | 2003-01-07 | 最終更新日 | 2018-10-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde Cell(Cambridge,Mass.), 111, 2002
|
|
4V4N
| Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... | 著者 | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | 登録日 | 2013-06-17 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
|
|
5OWD
| Vitamin D receptor complex | 分子名称: | (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A | 著者 | Rochel, N, Li, W. | 登録日 | 2017-08-31 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Sci Rep, 8, 2018
|
|
5OW7
| VDR complex | 分子名称: | (3~{S})-3-[(1~{S},3~{a}~{S},4~{E},7~{a}~{S})-7~{a}-methyl-4-[(2~{Z})-2-[(5~{S})-2-methylidene-5-oxidanyl-cyclohexylidene]ethylidene]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-1-yl]-3-oxidanyl-~{N}-propan-2-yl-butanamide, Nuclear receptor coactivator 1, Vitamin D3 receptor A | 著者 | Rochel, N, Li, W. | 登録日 | 2017-08-31 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Sci Rep, 8, 2018
|
|
5OW9
| Vitamin D receptor complex | 分子名称: | (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-heptan-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A | 著者 | Rochel, N, Li, W. | 登録日 | 2017-08-31 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Sci Rep, 8, 2018
|
|
7POJ
| Prodomain bound BMP10 crystal form 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 10, TETRAETHYLENE GLYCOL | 著者 | Guo, J, Yu, M, Li, W. | 登録日 | 2021-09-09 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
|
|
7PPB
| |
7PPA
| High resolution structure of bone morphogenetic protein receptor type II (BMPRII) extracellular domain in complex with BMP10 | 分子名称: | Bone morphogenetic protein 10, Bone morphogenetic protein receptor type-2, GLYCEROL | 著者 | Guo, J, Yu, M, Read, R.J, Li, W. | 登録日 | 2021-09-13 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
|
|
7POI
| Prodomain bound BMP10 crystal form 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 10, D(-)-TARTARIC ACID | 著者 | Guo, J, Yu, M, Li, W. | 登録日 | 2021-09-09 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
|
|
7PPC
| Ternary signalling complex of BMP10 bound to ALK1 and BMPRII | 分子名称: | Bone morphogenetic protein 10, Bone morphogenetic protein receptor type-2, Serine/threonine-protein kinase receptor R3 | 著者 | Guo, J, Yu, M, Read, R.J, Li, W. | 登録日 | 2021-09-13 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13, 2022
|
|
6XE0
| Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) | 分子名称: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. | 登録日 | 2020-06-11 | 公開日 | 2020-07-29 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
|
|
6EG5
| The structure of SB-1-202-tubulin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-chloropyrido[2,3-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, CALCIUM ION, ... | 著者 | Banerjee, A.K, Wang, Y, Chen, H, Miller, D, Li, W. | 登録日 | 2018-08-18 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The structure of SB-1-202/SB-2-204-tubulin complex To Be Published
|
|
6O5M
| Tubulin-RB3_SLD-TTL in complex with compound 10bb | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-03-04 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
|
|
6O5N
| Tubulin-RB3_SLD-TTL in complex with compound 10ab | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-03-04 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
|
|
6O61
| Tubulin-RB3_SLD-TTL in complex with compound ABI-231 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-03-05 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
|
|
6PC4
| Tubulin-RB3_SLD-TTL in complex with compound ABI-274 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-06-15 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. J.Med.Chem., 63, 2020
|
|
6SF3
| |
6WV5
| Human VKOR C43S mutant with vitamin K1 epoxide | 分子名称: | (2R,3R)-2-hydroxy-3-methyl-2-[(2E,7S)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-2,3-dihydronaphthalene-1,4-dione, Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WVH
| Human VKOR with Brodifacoum | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Brodifacoum, Vitamin K epoxide reductase, ... | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-06 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WV6
| Human VKOR with phenindione | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phenindione, Vitamin K epoxide reductase, ... | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WV3
| Human VKOR with warfarin | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, S-WARFARIN, Vitamin K epoxide reductase, ... | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WVB
| Takifugu rubripes VKOR-like with warfarin | 分子名称: | S-WARFARIN, Vitamin K epoxide reductase-like protein, termini restrained by green fluorescent protein | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WV4
| Human VKOR C43S with warfarin | 分子名称: | S-WARFARIN, Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein | 著者 | Liu, S, Sukumar, N, Li, W. | 登録日 | 2020-05-05 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.012 Å) | 主引用文献 | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
|
|
6WV8
| |
2K2G
| Solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor | 分子名称: | Macrophage metalloelastase, N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine, ZINC ION | 著者 | Markus, M.A, Dwyer, B, Wolfrom, S, Li, J, Li, W, Malakian, K, Wilhelm, J, Tsao, D.H.H. | 登録日 | 2008-04-01 | 公開日 | 2008-05-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor. J.Biomol.Nmr, 41, 2008
|
|