Vitamin D receptor complex

Summary for 5OWD

Related2HC4 5MX7
DescriptorVitamin D3 receptor A, Nuclear receptor coactivator 1, (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, ... (4 entities in total)
Functional Keywordsnuclear receptor, vitamin d, complex, transcription
Biological sourceDanio rerio (Zebrafish)
Cellular locationNucleus  Q9PTN2 Q15788
Total number of polymer chains2
Total molecular weight36235.37
Rochel, N.,Li, W. (deposition date: 2017-08-31, release date: 2018-02-07)
Primary citation
Lin, Z.,Marepally, S.R.,Goh, E.S.Y.,Cheng, C.Y.S.,Janjetovic, Z.,Kim, T.K.,Miller, D.D.,Postlethwaite, A.E.,Slominski, A.T.,Tuckey, R.C.,Peluso-Iltis, C.,Rochel, N.,Li, W.
Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities.
Sci Rep, 8:1478-1478, 2018
PubMed: 29367669 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-018-19183-7
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23020.4%3.1%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution