5OWD

Vitamin D receptor complex

Summary for 5OWD

Related2HC4 5MX7
DescriptorVitamin D3 receptor A, Nuclear receptor coactivator 1, (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, ... (4 entities in total)
Functional Keywordsnuclear receptor, vitamin d, complex, transcription
Biological sourceDanio rerio (Zebrafish)
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Cellular locationNucleus  Q9PTN2 Q15788
Total number of polymer chains2
Total molecular weight36235.37
Authors
Rochel, N.,Li, W. (deposition date: 2017-08-31, release date: 2018-02-07)
Primary citation
Lin, Z.,Marepally, S.R.,Goh, E.S.Y.,Cheng, C.Y.S.,Janjetovic, Z.,Kim, T.K.,Miller, D.D.,Postlethwaite, A.E.,Slominski, A.T.,Tuckey, R.C.,Peluso-Iltis, C.,Rochel, N.,Li, W.
Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities.
Sci Rep, 8:1478-1478, 2018
PubMed: 29367669 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-018-19183-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.151 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23020.4%3.1%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution