6WV4
Human VKOR C43S with warfarin
Summary for 6WV4
| Entry DOI | 10.2210/pdb6wv4/pdb |
| Descriptor | Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein, S-WARFARIN (3 entities in total) |
| Functional Keywords | vitamin k epoxide reductase (vkor), vitamin k, warfarin, superwarfarin, vitamin k expoxide(ko), membrane protein, oxidoreductase, fluorescent protein |
| Biological source | Aequorea victoria (Jellyfish) More |
| Total number of polymer chains | 1 |
| Total formula weight | 44489.70 |
| Authors | Liu, S.,Sukumar, N.,Li, W. (deposition date: 2020-05-05, release date: 2020-11-11, Last modification date: 2023-11-15) |
| Primary citation | Liu, S.,Li, S.,Shen, G.,Sukumar, N.,Krezel, A.M.,Li, W. Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371:-, 2021 Cited by PubMed: 33154105DOI: 10.1126/science.abc5667 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.012 Å) |
Structure validation
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