7PPC
Ternary signalling complex of BMP10 bound to ALK1 and BMPRII
Summary for 7PPC
Entry DOI | 10.2210/pdb7ppc/pdb |
Descriptor | Bone morphogenetic protein 10, Serine/threonine-protein kinase receptor R3, Bone morphogenetic protein receptor type-2, ... (4 entities in total) |
Functional Keywords | bmprii bmp10 alk1 signalling complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 147266.30 |
Authors | Guo, J.,Yu, M.,Read, R.J.,Li, W. (deposition date: 2021-09-13, release date: 2022-05-11, Last modification date: 2024-01-31) |
Primary citation | Guo, J.,Liu, B.,Thorikay, M.,Yu, M.,Li, X.,Tong, Z.,Salmon, R.M.,Read, R.J.,Ten Dijke, P.,Morrell, N.W.,Li, W. Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10. Nat Commun, 13:2395-2395, 2022 Cited by PubMed: 35504921DOI: 10.1038/s41467-022-30111-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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