7PPC

Ternary signalling complex of BMP10 bound to ALK1 and BMPRII

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008083	molecular_function	growth factor activity
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity
C	0005576	cellular_component	extracellular region
C	0008083	molecular_function	growth factor activity
D	0005576	cellular_component	extracellular region
D	0008083	molecular_function	growth factor activity
I	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
I	0005524	molecular_function	ATP binding
I	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
I	0016020	cellular_component	membrane
J	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
J	0005524	molecular_function	ATP binding
J	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
J	0016020	cellular_component	membrane
K	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
K	0005524	molecular_function	ATP binding
K	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
K	0016020	cellular_component	membrane
L	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
L	0005524	molecular_function	ATP binding
L	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
L	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IiaPpgYeayeCrGvC

Chain	Residue	Details
A	ILE341-CYS356

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Region: {"description":"Mediates specificity for BMP ligand"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	15
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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