8IVQ
| Cryo-EM structure of mouse BIRC6, Global map | 分子名称: | Isoform 2 of Baculoviral IAP repeat-containing protein 6 | 著者 | Liu, S, Jiang, T, Bu, F, Zhao, J, Wang, G, Li, N, Gao, N, Qiu, X. | 登録日 | 2023-03-28 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy. Nat Commun, 15, 2024
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5HH9
| Structure of PvdN from Pseudomonas aeruginosa | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, PvdN | 著者 | Xia, H, Bai, G, Liu, S, Li, N, Xu, S, Chen, K, Yao, Q, Gu, L. | 登録日 | 2016-01-10 | 公開日 | 2017-01-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural and Biochemical Characterization of a Novel L-Cystine Desulfurase involved in the biosynthesis of the major siderophore pyoverdine in Pseudomonas aeruginosa To Be Published
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5DP4
| Crystal Structure of EV71 3C Proteinase in complex with compound 3 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-{[(2S)-2-methyl-3-phenylpropanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP6
| Crystal Structure of EV71 3C Proteinase in complex with compound 7 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-{[N-(3-cyclopropylpropanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP9
| Crystal Structure of EV71 3C Proteinase in complex with compound 9 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-[(N-{[(cyclobutylmethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP8
| Crystal Structure of EV71 3C Proteinase in complex with compound 8 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-[(N-{[(2-cyclopropylethyl)amino](oxo)acetyl}-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DPA
| Crystal Structure of EV71 3C Proteinase in complex with compound 6 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-[(N-acetyl-L-phenylalanyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP5
| Crystal Structure of EV71 3C Proteinase in complex with compound 4 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-{[(2R,5S)-5-amino-2-(4-fluorobenzyl)-6-methyl-4-oxoheptanoyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2016-04-06 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP7
| Crystal Structure of EV71 3C Proteinase in complex with compound 5 | 分子名称: | 3C proteinase, ethyl (2Z,4S)-4-{[N-(3-methylbutanoyl)-L-phenylalanyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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5DP3
| Crystal Structure of EV71 3C Proteinase in complex with compound 2 | 分子名称: | 3C proteinase, ethyl (4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-[(3-phenylpropanoyl)amino]pent-2-enoate | 著者 | Wu, C, Zhang, L, Li, P, Cai, Q, Peng, X, Li, N, Cai, Y, Li, J, Lin, T. | 登録日 | 2015-09-12 | 公開日 | 2016-03-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71 Biochim.Biophys.Acta, 1860, 2016
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7Y1B
| 3.2 angstrom cryo-EM structure of extracellular region of mouse Basigin-2 in complex with the Fab fragment of antibody 6E7F1 | 分子名称: | Heavy chain of 6E7F1, Isoform 2 of Basigin, Light chain of 6E7F1 | 著者 | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin To Be Published
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7Y1Q
| 5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1 | 分子名称: | Isoform 2 of Basigin, Monocarboxylate transporter 1 | 著者 | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (5.03 Å) | 主引用文献 | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2 To Be Published
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3TLQ
| Crystal structure of EAL-like domain protein YdiV | 分子名称: | GLYCEROL, PHOSPHATE ION, Regulatory protein YdiV | 著者 | Li, B, Li, N, Wang, F, Guo, L, Liu, C, Zhu, D, Xu, S, Gu, L. | 登録日 | 2011-08-30 | 公開日 | 2012-09-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility Nucleic Acids Res., 40, 2012
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6J0B
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath-tube complex in extended state | 分子名称: | Pvc1, Pvc2 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-23 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0C
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath complex in contracted state | 分子名称: | Pvc2 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-23 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0F
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath/tube terminator in extended state | 分子名称: | Pvc1, Pvc16 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-24 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0N
| Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry | 分子名称: | Pvc1, Pvc11, Pvc12, ... | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-25 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0M
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry) | 分子名称: | Pvc8 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-24 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6JXR
| Structure of human T cell receptor-CD3 complex | 分子名称: | T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, T-cell surface glycoprotein CD3 delta chain, ... | 著者 | Dong, D, Zheng, L, Lin, J, Zhu, Y, Li, N, Zhang, B, Xie, S, Zheng, J, Wang, Y, Gao, N, Huang, Z. | 登録日 | 2019-04-24 | 公開日 | 2019-09-11 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of assembly of the human T cell receptor-CD3 complex. Nature, 573, 2019
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6IV6
| Cryo-EM structure of AcrVA5-acetylated MbCas12a in complex with crRNA | 分子名称: | RNA (59-MER), nuclease | 著者 | Dong, L, Li, N, Guan, X, Zhu, Y, Gao, N, Huang, Z. | 登録日 | 2018-12-02 | 公開日 | 2019-04-10 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | An anti-CRISPR protein disables type V Cas12a by acetylation. Nat. Struct. Mol. Biol., 26, 2019
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3J3T
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | 登録日 | 2013-04-18 | 公開日 | 2013-05-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J3R
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | 登録日 | 2013-04-18 | 公開日 | 2013-05-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine J.Biol.Chem., 288, 2013
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3J3U
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | 登録日 | 2013-04-18 | 公開日 | 2013-05-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J3S
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | 登録日 | 2013-04-18 | 公開日 | 2013-05-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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8ERH
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