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7Y1B

3.2 angstrom cryo-EM structure of extracellular region of mouse Basigin-2 in complex with the Fab fragment of antibody 6E7F1

Summary for 7Y1B
Entry DOI10.2210/pdb7y1b/pdb
EMDB information33559
DescriptorIsoform 2 of Basigin, Heavy chain of 6E7F1, Light chain of 6E7F1 (3 entities in total)
Functional Keywordstransporter, glucose metabolism, monocarboxylic acid transport, alpha helical tms, transport protein
Biological sourceMus musculus (house mouse)
More
Total number of polymer chains3
Total formula weight80907.63
Authors
Zhang, H.,Yang, X.,Xue, Y.,Huang, Y.,Mo, X.,Zhang, H.,Li, N.,Gao, N.,Li, X.,Wang, S.,Gao, Y.,Liao, J. (deposition date: 2022-06-08, release date: 2023-06-14)
Primary citationZhang, H.,Yang, X.,Xue, Y.,Huang, Y.,Mo, Y.,Zhang, H.,Li, N.,Gao, N.,Li, X.,Wang, S.,Gao, Y.,Liao, J.
Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.23 Å)
Structure validation

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