4LWH
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![BU of 4lwh by Molmil](/molmil-images/mine/4lwh) | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ5 | Descriptor: | Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazol-5-yl}cyclopropanecarboxamide | Authors: | Li, J, Shi, F, Xiong, B, He, J. | Deposit date: | 2013-07-27 | Release date: | 2014-07-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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3T2S
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![BU of 3t2s by Molmil](/molmil-images/mine/3t2s) | HSP90 N-terminal domain bound to AGS | Descriptor: | Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Li, J. | Deposit date: | 2011-07-23 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | HSP90 N-terminal domain bound to AGS To be published
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4JN9
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![BU of 4jn9 by Molmil](/molmil-images/mine/4jn9) | Crystal structure of the DepH | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ... | Authors: | Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E. | Deposit date: | 2013-03-14 | Release date: | 2014-04-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis. Sci Rep, 4, 2014
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7F02
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![BU of 7f02 by Molmil](/molmil-images/mine/7f02) | Cytochrome c-type biogenesis protein CcmABCD from E. coli | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | Deposit date: | 2021-06-03 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7F03
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![BU of 7f03 by Molmil](/molmil-images/mine/7f03) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | Deposit date: | 2021-06-03 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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4JNA
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![BU of 4jna by Molmil](/molmil-images/mine/4jna) | Crystal structure of the DepH complex with dimethyl-FK228 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ... | Authors: | Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E. | Deposit date: | 2013-03-14 | Release date: | 2014-03-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis. Sci Rep, 4, 2014
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5ZVD
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![BU of 5zvd by Molmil](/molmil-images/mine/5zvd) | |
5ZVH
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![BU of 5zvh by Molmil](/molmil-images/mine/5zvh) | |
5ZCK
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![BU of 5zck by Molmil](/molmil-images/mine/5zck) | Structure of the RIP3 core region | Descriptor: | SODIUM ION, peptide from Receptor-interacting serine/threonine-protein kinase 3 | Authors: | Li, J, Wu, H. | Deposit date: | 2018-02-18 | Release date: | 2018-04-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.271 Å) | Cite: | The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. Cell, 173, 2018
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5ZVG
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![BU of 5zvg by Molmil](/molmil-images/mine/5zvg) | |
4PY4
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![BU of 4py4 by Molmil](/molmil-images/mine/4py4) | |
5X3V
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![BU of 5x3v by Molmil](/molmil-images/mine/5x3v) | Structure of human SHMT2 protein mutant | Descriptor: | SULFATE ION, Serine hydroxymethyltransferase, mitochondrial | Authors: | Li, J, Sheng, J. | Deposit date: | 2017-02-09 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of human SHMT2 protein mutant To Be Published
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5ZVE
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![BU of 5zve by Molmil](/molmil-images/mine/5zve) | |
3T1K
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![BU of 3t1k by Molmil](/molmil-images/mine/3t1k) | HSP90 N-terminal domain bound to ANP | Descriptor: | Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Li, J. | Deposit date: | 2011-07-22 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | HSP90 N-terminal domain bound to ANP To be published
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2FCO
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![BU of 2fco by Molmil](/molmil-images/mine/2fco) | Crystal Structure of Bacillus stearothermophilus PrfA-Holliday Junction Resolvase | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, recombination protein U (penicillin-binding protein related factor A) | Authors: | Li, J, Jedrzejas, M.J. | Deposit date: | 2005-12-12 | Release date: | 2006-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure, flexibility, and mechanism of the Bacillus stearothermophilus RecU Holliday junction resolvase. Proteins, 68, 2007
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7U20
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![BU of 7u20 by Molmil](/molmil-images/mine/7u20) | Crystal structure of human METTL1 and WDR4 complex | Descriptor: | SULFATE ION, tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | Authors: | Li, J, Nowak, R.P, Fischer, E.S, Gregory, R. | Deposit date: | 2022-02-22 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4. Nature, 613, 2023
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4JOC
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![BU of 4joc by Molmil](/molmil-images/mine/4joc) | |
4JOB
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![BU of 4job by Molmil](/molmil-images/mine/4job) | |
8I54
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![BU of 8i54 by Molmil](/molmil-images/mine/8i54) | Lb2Cas12a RNA DNA complex | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*GP*TP*GP*CP*TP*TP*TP*A)-3'), Lb2Cas12a, ... | Authors: | Li, J, Sivaraman, J, Satoru, M. | Deposit date: | 2023-01-24 | Release date: | 2023-02-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21, 2023
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5WSU
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![BU of 5wsu by Molmil](/molmil-images/mine/5wsu) | Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM | Descriptor: | Calmodulin, Unconventional myosin-VIIa | Authors: | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | Deposit date: | 2016-12-08 | Release date: | 2017-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension Structure, 25, 2017
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4JOD
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![BU of 4jod by Molmil](/molmil-images/mine/4jod) | |
5WST
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![BU of 5wst by Molmil](/molmil-images/mine/5wst) | Crystal structure of Myo7a SAH | Descriptor: | Unconventional myosin-VIIa | Authors: | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | Deposit date: | 2016-12-08 | Release date: | 2017-06-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension Structure, 25, 2017
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5X07
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![BU of 5x07 by Molmil](/molmil-images/mine/5x07) | Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site | Descriptor: | DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta | Authors: | Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y. | Deposit date: | 2017-01-20 | Release date: | 2017-08-16 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site Biochemistry, 56, 2017
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8WY4
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![BU of 8wy4 by Molmil](/molmil-images/mine/8wy4) | GajA tetramer with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA | Authors: | Li, J, Wang, Z, Wang, L. | Deposit date: | 2023-10-30 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X5N
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![BU of 8x5n by Molmil](/molmil-images/mine/8x5n) | Tetramer Gabija with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ... | Authors: | Li, J, Wang, Z, Wang, L. | Deposit date: | 2023-11-17 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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