8I54
Lb2Cas12a RNA DNA complex
Summary for 8I54
| Entry DOI | 10.2210/pdb8i54/pdb |
| EMDB information | 35191 |
| Descriptor | Lb2Cas12a, RNA (33-MER), DNA (25-MER), ... (4 entities in total) |
| Functional Keywords | complex, antimicrobial protein |
| Biological source | Lachnospiraceae bacterium MA2020 More |
| Total number of polymer chains | 4 |
| Total formula weight | 162178.66 |
| Authors | Li, J.,Sivaraman, J.,Satoru, M. (deposition date: 2023-01-24, release date: 2023-02-22, Last modification date: 2023-05-03) |
| Primary citation | Jianwei, L.,Jobichen, C.,Machida, S.,Meng, S.,Read, R.J.,Hongying, C.,Jian, S.,Yuan, Y.A.,Sivaraman, J. Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21:e3002023-e3002023, 2023 Cited by PubMed: 36917574DOI: 10.1371/journal.pbio.3002023 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.95 Å) |
Structure validation
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