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PDB: 833 件

4LWH
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Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ5
分子名称: Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazol-5-yl}cyclopropanecarboxamide
著者Li, J, Shi, F, Xiong, B, He, J.
登録日2013-07-27
公開日2014-07-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
3T2S
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BU of 3t2s by Molmil
HSP90 N-terminal domain bound to AGS
分子名称: Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Li, J.
登録日2011-07-23
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献HSP90 N-terminal domain bound to AGS
To be published
4JN9
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Crystal structure of the DepH
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
著者Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
登録日2013-03-14
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
7F02
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Cytochrome c-type biogenesis protein CcmABCD from E. coli
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ...
著者Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
登録日2021-06-03
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
7F03
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Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ...
著者Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
登録日2021-06-03
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
4JNA
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Crystal structure of the DepH complex with dimethyl-FK228
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
著者Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
登録日2013-03-14
公開日2014-03-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
5ZVD
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BU of 5zvd by Molmil
The crystal structure of NSun6 from Pyrococcus horikoshii
分子名称: 389aa long hypothetical nucleolar protein
著者Li, J, Liu, R.J, Wang, E.D.
登録日2018-05-10
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs.
Nucleic Acids Res., 47, 2019
5ZVH
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The crystal structure of NSun6 from Pyrococcus horikoshii with SFG
分子名称: 389aa long hypothetical nucleolar protein, SINEFUNGIN
著者Li, J, Liu, R.J, Wang, E.D.
登録日2018-05-10
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs.
Nucleic Acids Res., 47, 2019
5ZCK
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Structure of the RIP3 core region
分子名称: SODIUM ION, peptide from Receptor-interacting serine/threonine-protein kinase 3
著者Li, J, Wu, H.
登録日2018-02-18
公開日2018-04-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.271 Å)
主引用文献The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.
Cell, 173, 2018
5ZVG
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The crystal structure of NSun6 from Pyrococcus horikoshii with SAM
分子名称: 389aa long hypothetical nucleolar protein, S-ADENOSYLMETHIONINE
著者Li, J, Liu, R.J, Wang, E.D.
登録日2018-05-10
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs.
Nucleic Acids Res., 47, 2019
4PY4
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BU of 4py4 by Molmil
Crystal structure of human poly(ADP-ribose) polymerase 14, catalytic domain in complex with an inhibitor XL2
分子名称: 2-({4-[(1R)-1-(dimethylamino)ethyl]phenyl}amino)-6-fluoro-1,3-benzothiazole-4-carboxamide, Poly [ADP-ribose] polymerase 14
著者Li, J, Xu, Y.
登録日2014-03-26
公開日2015-04-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors
Tetrahedron, 70, 2017
5X3V
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Structure of human SHMT2 protein mutant
分子名称: SULFATE ION, Serine hydroxymethyltransferase, mitochondrial
著者Li, J, Sheng, J.
登録日2017-02-09
公開日2018-02-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of human SHMT2 protein mutant
To Be Published
5ZVE
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BU of 5zve by Molmil
The crystal structure of NSun6 from Pyrococcus horikoshii with SAH
分子名称: 389aa long hypothetical nucleolar protein, S-ADENOSYL-L-HOMOCYSTEINE
著者Li, J, Liu, R.J, Wang, E.D.
登録日2018-05-10
公開日2018-12-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.178 Å)
主引用文献Archaeal NSUN6 catalyzes m5C72 modification on a wide-range of specific tRNAs.
Nucleic Acids Res., 47, 2019
3T1K
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BU of 3t1k by Molmil
HSP90 N-terminal domain bound to ANP
分子名称: Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Li, J.
登録日2011-07-22
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献HSP90 N-terminal domain bound to ANP
To be published
2FCO
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BU of 2fco by Molmil
Crystal Structure of Bacillus stearothermophilus PrfA-Holliday Junction Resolvase
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, recombination protein U (penicillin-binding protein related factor A)
著者Li, J, Jedrzejas, M.J.
登録日2005-12-12
公開日2006-11-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure, flexibility, and mechanism of the Bacillus stearothermophilus RecU Holliday junction resolvase.
Proteins, 68, 2007
7U20
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BU of 7u20 by Molmil
Crystal structure of human METTL1 and WDR4 complex
分子名称: SULFATE ION, tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
著者Li, J, Nowak, R.P, Fischer, E.S, Gregory, R.
登録日2022-02-22
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
4JOC
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BU of 4joc by Molmil
Crystal structure of human lysophosphatidic acid phosphatase type 6 complexed with Malonate
分子名称: Lysophosphatidic acid phosphatase type 6, MALONIC ACID
著者Li, J.
登録日2013-03-18
公開日2013-07-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6
Protein Cell, 4, 2013
4JOB
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BU of 4job by Molmil
Crystal structure of human lysophosphatidic acid phosphatase type 6 complexed with L-(+)-tartrate
分子名称: L(+)-TARTARIC ACID, Lysophosphatidic acid phosphatase type 6
著者Li, J.
登録日2013-03-18
公開日2013-07-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.171 Å)
主引用文献Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6
Protein Cell, 4, 2013
8I54
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BU of 8i54 by Molmil
Lb2Cas12a RNA DNA complex
分子名称: DNA (25-MER), DNA (5'-D(*AP*GP*TP*GP*CP*TP*TP*TP*A)-3'), Lb2Cas12a, ...
著者Li, J, Sivaraman, J, Satoru, M.
登録日2023-01-24
公開日2023-02-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
Plos Biol., 21, 2023
5WSU
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BU of 5wsu by Molmil
Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM
分子名称: Calmodulin, Unconventional myosin-VIIa
著者Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M.
登録日2016-12-08
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
4JOD
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BU of 4jod by Molmil
Crystal structure of human lysophosphatidic acid phosphatase type 6 complexed with Tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Lysophosphatidic acid phosphatase type 6
著者Li, J.
登録日2013-03-18
公開日2013-07-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6.
Protein Cell, 4, 2013
5WST
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BU of 5wst by Molmil
Crystal structure of Myo7a SAH
分子名称: Unconventional myosin-VIIa
著者Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M.
登録日2016-12-08
公開日2017-06-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
5X07
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BU of 5x07 by Molmil
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta
著者Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y.
登録日2017-01-20
公開日2017-08-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site
Biochemistry, 56, 2017
8WY4
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GajA tetramer with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA
著者Li, J, Wang, Z, Wang, L.
登録日2023-10-30
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X5N
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Tetramer Gabija with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ...
著者Li, J, Wang, Z, Wang, L.
登録日2023-11-17
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024

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件を2024-08-07に公開中

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