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PDB: 375 件

7EVR
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Crystal structure of hnRNP L RRM2 in complex with SETD2
分子名称: Heterogeneous nuclear ribonucleoprotein L, SHI domain from Histone-lysine N-methyltransferase SETD2
著者Li, F.D, Wang, S.M.
登録日2021-05-22
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.
Nat Commun, 12, 2021
7EVS
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Crystal structure of hnRNP LL RRM2 in complex with SETD2
分子名称: Heterogeneous nuclear ribonucleoprotein L-like, SHI domain from Histone-lysine N-methyltransferase SETD2, SULFATE ION
著者Li, F.D, Wang, S.M.
登録日2021-05-22
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.
Nat Commun, 12, 2021
6KI6
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Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region
分子名称: B-cell lymphoma/leukemia 11A, DNA (5'-D(*AP*TP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*A)-3'), ...
著者Li, F.D, Yang, Y, Shi, Y.Y.
登録日2019-07-17
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the recognition of gamma-globin gene promoter by BCL11A.
Cell Res., 29, 2019
8VA1
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S. aureus TarL H300N in complex with CDP-ribitol (single tetramer)
分子名称: CDP-ribitol, Teichoic acid ribitol-phosphate polymerase TarL
著者Li, F.K.K, Worrall, L.J, Strynadka, N.C.J.
登録日2023-12-10
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8V33
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Crystal structure of S. aureus TarL N-terminal domain
分子名称: SUCCINIC ACID, Teichoic acid ribitol-phosphate polymerase TarL
著者Li, F.K.K, Strynadka, N.C.J.
登録日2023-11-26
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8WU6
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Structure of a Nerylneryl Diphosphate Synthase from Solanum lycopersicum
分子名称: Nerylneryl diphosphate synthase CPT2, chloroplastic
著者Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B.
登録日2023-10-20
公開日2024-05-08
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase.
Angew.Chem.Int.Ed.Engl., 63, 2024
8WU7
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Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus
分子名称: Isoprenyl transferase
著者Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B.
登録日2023-10-20
公開日2024-05-08
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase.
Angew.Chem.Int.Ed.Engl., 63, 2024
4GNG
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Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide
分子名称: GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ...
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GND
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Crystal Structure of NSD3 tandem PHD5-C5HCH domains
分子名称: Histone-lysine N-methyltransferase NSD3, ZINC ION
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4H14
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Crystal Structure of Bovine Coronavirus Spike Protein Lectin Domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
著者Li, F.
登録日2012-09-10
公開日2012-10-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of bovine coronavirus spike protein lectin domain.
J.Biol.Chem., 287, 2012
4GNF
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Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15
分子名称: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GNE
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Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7
分子名称: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
8HR5
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Cryo-EM structure of the CnCas12f1-sgRNA-DNA complex
分子名称: DNA (28-MER), DNA (5'-D(*TP*AP*AP*CP*CP*TP*AP*AP*TP*AP*GP*AP*TP*GP*TP*GP*AP*A)-3'), Transposase, ...
著者Li, F, Ji, Q.
登録日2022-12-14
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structure and engineering of miniature Clostridium novyi CRISPR-Cas12f1 with rare C-rich PAM specificity
To Be Published
5YB5
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The complex crystal structure of VrEH2 mutant M263N with SNO
分子名称: (S)-PARA-NITROSTYRENE OXIDE, Epoxide hydrolase
著者Li, F.L, Chen, F.F, Chen, Q, Kong, X.D, Yu, H.L, Xu, J.H.
登録日2017-09-03
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
5YJ3
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Crystal structure of TZAP and telomeric DNA complex
分子名称: DNA (5'-D(*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Telomere zinc finger-associated protein, ...
著者Li, F, Zhao, Y.
登録日2017-10-07
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.845 Å)
主引用文献The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA.
Cell Res., 28, 2018
5Y6Y
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The crystal structure of VrEH2 mutant M263N
分子名称: Epoxide hydrolase
著者Li, F.L, Yu, H.L, Chen, Q, Kong, X.D, Zhou, J.H, Xu, J.H.
登録日2017-08-15
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
7UKJ
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In situ cryo-EM structure of bacteriophage Sf6 portal:gp7 complex at 2.7A resolution
分子名称: Gene 14 protein
著者Li, F, Cingolani, G, Hou, C.
登録日2022-04-01
公開日2022-12-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
6AKJ
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The crystal structure of EMC complex
分子名称: Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein, SULFATE ION
著者Li, F.
登録日2018-09-01
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing.
Nat Commun, 10, 2019
5XM6
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BU of 5xm6 by Molmil
the overall structure of VrEH2
分子名称: Epoxide hydrolase
著者Li, F.L, Kong, X.D, Yu, H.L, Shang, Y.P, Zhou, J.H, Xu, J.H.
登録日2017-05-12
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation
Acs Catalysis, 8, 2018
7CG2
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Vigna radiata Epoxide hydrolase mutant
分子名称: Epoxide hydrolase
著者Li, F.L, Yu, H.L, Xu, J.H.
登録日2020-06-30
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds
Adv.Synth.Catal., 362, 2021
7CG6
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Vigna radiata Epoxide hydrolase mutant M263Q
分子名称: Epoxide hydrolase
著者Li, F.L, Yu, H.L, Xu, J.H.
登録日2020-06-30
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds
Adv.Synth.Catal., 362, 2021
7DBE
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BU of 7dbe by Molmil
Structure of a novel transaminase
分子名称: 1,2-ETHANEDIOL, PYRIDOXAL-5'-PHOSPHATE, branched-chain amino acid aminotransferase
著者Li, F.L, Yu, H.M.
登録日2020-10-20
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Biochemical and Structural Characterization of an (R)-Selective Transaminase in the Asymmetric Synthesis of Chiral Hydroxy Amines.
Adv.Synth.Catal., 2021
7CNC
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cystal structure of human ERH in complex with DGCR8
分子名称: Enhancer of rudimentary homolog, Microprocessor complex subunit DGCR8
著者Li, F, Shen, S.
登録日2020-07-30
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8.
Nucleic Acids Res., 48, 2020
3KBH
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Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein
著者Wu, K, Li, W, Peng, G, Li, F.
登録日2009-10-20
公開日2009-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor.
Proc.Natl.Acad.Sci.USA, 106, 2009
5JCP
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RhoGAP domain of ARAP3 in complex with RhoA in the transition state
分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bao, H, Li, F, Wang, C, Wang, N, Jiang, Y, Tang, Y, Wu, J, Shi, Y.
登録日2016-04-15
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016

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